In order to study the influence of jet surface under the circumstance of multifactor coupling, an extension module of coupling elements and coupling mode between main flow field velocity and jet velocity, as well as high configuration of jet hole and coupling arrangement of the bottom of the jet hole was built by using the basic principle of extension. The drag reduction characteristics of jet surface under conditions of multifactor coupling were numerically simulated with standard k-ε turbulence model. The reasons for reducing the viscous resistance and drag reduction rate of the jet surface were analyzed, and the controlling behavior of jet surface towards the flow field of the boundary layer of the wall near the jet holes was revealed. The results show that under the condition of multi-factor coupling, the jet surface has a better drag reduction effect, and the best drag reduction rate is 27.69%. The jet surface under conditions of multi-factor coupling changes the shear stress distribution of walls, and affects the structure of boundary layer. Meanwhile, vortexes formed in the downstream of jet holes alter the thickness of boundary layer, which leads to the reduction of viscous resistance near the wall, and makes the jet surface to have the characteristics of drag reduction.