Abstract： To solve the problem of the overuse of communication optimization techniques—communication pipeline and message aggregation—in MPSoC (Multiprocessor System-on-chip), which may increase the synchronization cost and lead to system performance degradation, an ILP (integer linear programming) based strategy was proposed. The strategy can employ communication pipeline and message aggregation techniques appropriately, considering communication optimization as well as synchronization optimization, to achieve optimal system performance. Experimental results show that the proposed strategy can take the advantage of the communication optimization techniques and obtain significant performance improvements.