Abstract： Based on the current domestic situation that the welding of aero tube is mainly the manual gas tungsten arc welding, a digital welding of aero tube was proposed. The hand-eye calibration of robot involved in the system was studied. By establishing the camera coordinate system in the installation distance of META seam tracking sensor, the handeye calibration is completed using a three dimensional measuring machine. The results show that the calibration accuracy of this method is ±0.4 mm, which meets the requirement of the digital welding of aero tube.