Abstract： Due to the restriction of cost, storage space and carrying ability for support resources, and aimed at the multiconstraints targets for the optimization scheme for space navigation carrying spare parts, the optimization scheme of orbiter carrying spare parts at the task preparation stage before flying was deemed as a study background. The target expected back order of configuration optimization model of spare parts was established based on multiconstraints, such as cost, mass, and volume of spare parts. The initial configuration scheme of spare parts could be obtained by setting the initial value of the initial factor. At the same time, different constraint elements were converted into the scale of spares resource constraint by introducing Lagrange constraint factor. The configuration optimization model was updated by introducing the Marginal algorithm. Finally, the configuration optimization scheme of spare parts was obtained by comparing the results of six projects. In the given example, the calculated result was analyzed, and the feasibility of the proposed method was verified.