Abstract： A zero wear model was established for the design of internal combustion engine sliding bearing, with the consideration of the lubrication model, the asperity contact model, the multibody dynamics model and the zero wear experiment criterion. The safety factor for zero wear was calculated to predict the reliability of wear. The zero wear model was applied to the main bearing design for a sixcylinder diesel engine. The results show that the distribution of zero wear safety factor can be predicted by using this method. This paper can provide theoretical guidance for zero wear design of bearing.