目的：探讨采用母亲体内IgG抗A（抗B）的效价积分对新生儿溶血病严重程度进行预判的价值。方法：检测27例新生儿溶血病患儿的红细胞计数、血红蛋白、红细胞比容和其母亲的IgG抗A（抗B）效价、效价积分,对其进行趋势线计算和相关性分析。结果：母亲的IgG抗A（抗B）效价积分和效价上升时,患儿的红细胞计数、血红蛋白含量、红细胞比容都下降;而在母亲抗体效价相同的情况下,效价积分越高,患儿的红细胞计数、血红蛋白含量、红细胞比容越低。相关性分析显示,在对新生儿溶血病患儿的贫血程度的预判中,效价积分与患儿血红蛋白含量间的相关系数为-0.966,其母亲的IgG抗A（抗B）效价积分与患儿贫血程度间的相关性比抗体效价更密切。结论：孕妇IgG抗A（抗B）的效价积分在预判患儿贫血的严重程度中具有一定临床价值。

Objective: To study the correlation of IgG anti-A/B titer score and the severity of hemolytic disease of newborn. Methods: The red blood cell count, hemoglobin and hematocrit value of 27 newborn with hemolytic disease and the IgG anti-A/B titer and titer score of their mother were measured and their correlations were analyzed. Results: With the increase in IgG anti-A/B titer and titer score of mother, the red blood cell count, hemoglobin and hematocrit values of newborn with hemolytic disease decreased. At the same IgG anti-A/B titer, the higher the titer score, the lower the red blood count, hemoglobin and hematocrit value were. Conclusions: According to the correlation analysis, the titer score is more closely related to the severity of hemolytic disease of newborn. For hemoglobin, the correlation coefficient was -0.966. The IgG anti-A/B titer score was of more clinical significance in predicting the severity of hemolytic disease in newborn.