Obinutuzumab for primary membranous nephropathy: can it be a new option beyond rituximab?

  • CHEN Duqun ,
  • CHENG Zhen
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Received date: 2026-06-20

  Revised date: 2026-06-21

  Accepted date: 2026-07-10

  Online published: 2026-08-19

Copyright

Copyright © 2026 Journal of Internal Medicine Concepts & Practice. All rights reserved.

Cite this article

CHEN Duqun , CHENG Zhen . Obinutuzumab for primary membranous nephropathy: can it be a new option beyond rituximab?[J]. Journal of Internal Medicine Concepts & Practice, 2026 , 21(03) : 248 -249 . DOI: 10.16138/j.1673-6087.2026.03.08

References

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[2] 陈独群, 涂远茂, 李辉, 等. 奥妥珠单抗治疗难治及高危磷脂酶A2受体相关膜性肾病的疗效观察[J]. 肾脏病与透析肾移植杂志, 2025, 34(1): 1-7.
  Chen DQ, Tu YM, Li H, et al. Obinutuzumab in treatment of high risk or refractory phospholipase A2 receptor associated membranous nephropathy[J]. Chin J Nephrol Dial Transplant, 2025, 34(1): 1-7.
[3] Hu X, Zhang M, Xu J, et al. Comparison of obinutuzumab and rituximab for treating primary membranous nephropathy[J]. Clin J Am Soc Nephrol, 2024, 19(12): 1594-1602.
[4] Xu M, Wang Y, Wu M, et al. Obinutuzumab versus rituximab for the treatment of refractory primary membranous nephropathy[J]. Nephrol Dial Transplant, 2025, 40(5): 978-986.
[5] 陈独群, 王晶晶, 邱丹丹, 等. 奥妥珠单抗治疗极高危磷脂酶A2受体相关膜性肾病患者的疗效观察[J]. 肾脏病与透析肾移植杂志, 2026, 35(2): 101-106.
  Chen DQ, Wang JJ, Qiu DD, et al. Obinutuzumab in the treatment of phospholipase A2 receptor associated membranous nephropathy with very high risk: an observational study[J]. Chin J Nephrol Dial Transplant, 2026, 35(2): 101-106.
[6] Cui Z, Wei M, Li P, et al. Efficacy and safety of MIL62, a Glycoengineered Type Ⅱ Anti-CD20 antibody, in primary membranous nephropathy:a phase 3, randomized, controlled trial [C/OL]. (2025-11-08)[2026-07-08]. https://www.asn-online.org/education/kidneyweek/2025/program-abstract.aspx?controlId=4401259.
[7] Lurie A, Daneii P, Khan S, et al. Obinutuzumab versus rituximab for the treatment of primary membranous nephropathy: a systematic review and meta-analysis[J]. Life (Basel), 2026, 16(3): 434.
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