外科理论与实践

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2023 , Vol. 28 >Issue 01: 31 - 35

DOI: https://doi.org/10.16139/j.1007-9610.2023.01.05

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动静脉结合术前化疗在进展期胃癌治疗中的应用

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  • 中国人民解放军东部战区总医院普通外科， 江苏 南京 210002

收稿日期: 2022-12-12

  网络出版日期: 2023-03-25

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Preoperative chemotherapy through intra-arterial combined with intra-venous administration in treatment of advanced gastric cancer

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  • Department of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Jiangsu Nanjing 210002, China

Received date: 2022-12-12

  Online published: 2023-03-25

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摘要

围术期化疗是进展期胃癌综合治疗的重要组成部分。有别于常规的全身化疗，动静脉结合术前化疗在联合用药的基础上，根据药物作用特点，对给药方式进一步优化，在本中心已有20余年的临床应用和研究历史。本文将从理论基础、发展过程、治疗优势和临床研究进行介绍。通过回顾临床与基础研究，阐述其临床治疗效果和可能的作用机制。

关键词： 动静脉结合术前化疗; 进展期胃癌; 动脉介入化疗; 新辅助化疗

本文引用格式

李国立, 郭飞龙 . 动静脉结合术前化疗在进展期胃癌治疗中的应用[J]. 外科理论与实践, 2023 , 28(01) : 31 -35 . DOI: 10.16139/j.1007-9610.2023.01.05

Abstract

Perioperative chemotherapy has been an important part of the comprehensive treatment of advanced gastric cancer. Different from the conventional systemic chemotherapy, preoperative chemotherapy through intra-arterial combined with intra-venous further optimized delivery routes according to characteristics of different drugs on the basis of combination chemotherapy，which has been studied and practiced at our center for more than 20 years. In this review, we will introduce this chemotherapy from the aspects of theoretical basis, development process, treatment advantages, and clinical research. The clinical efficacy and possible treatment mechanisms will be discussed through looking back on both clinic and basic study.

Key words： Preoperative chemotherapy through intra-arterial combined with intra-venous administration; Advanced gastric cancer; Intra-arterial chemotherapy; Neoadjuvant chemotherapy

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