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大语言模型赋能乳腺外科精准决策与全周期病人管理

  • 朱能军 ,
  • 曹健 ,
  • 陈小松 ,
  • 朱思吉
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  • 1 上海大学计算机工程与科学学院, 上海 200444
    2 上海交通大学计算机学院, 上海 200240
    3 上海交通大学医学院附属瑞金医院普外科 乳腺疾病诊治中心, 上海 200025
作者贡献/Authors’ contributions

朱能军负责收集资料、查阅文献、汇总、撰稿;曹健负责文章修改、审校、文章思路指导;陈小松负责文章修改、审校、提供意见;朱思吉负责文章修改、审校、提供意见。所有作者均阅读并确认最终稿。

曹健,E-mail: cao-jian@sjtu.edu.cn

收稿日期: 2025-04-22

  网络出版日期: 2026-08-11

基金资助

上海体育科技项目(26Q013);上海市卫健委医学新技术研究与转化种子计划重点项目(2025ZZ1009);上海市卫健委智慧医疗专项(2025ZHYL003);国家自然科学基金(82573726)

Large language models empower precision decision-making in breast surgery and whole-cycle patient management

  • ZHU Nengjun ,
  • CAO Jian ,
  • CHEN Xiaosong ,
  • ZHU Siji
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  • 1 School of Computer Engineering and Science, Shanghai University, Shanghai 200444, China
    2 School of Computer Science, Shanghai Jiao Tong University, Shanghai 200240, China
    3 Department of General Surgery, Comprehensive Breast Health Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Received date: 2025-04-22

  Online published: 2026-08-11

摘要

早期乳腺癌诊疗具有病程长、异质性强、数据多源异构及决策动态演变等特点,传统多学科诊疗(MDT)决策模式面临效率低、全周期管理断层等挑战。大语言模型(LLM)凭借处理非结构化文本、整合多源数据及辅助临床推理的优势,为解决上述问题提供了新路径。本文阐述LLM在乳腺癌MDT决策中的应用价值,重点分析个体化治疗推荐智能体、多智能体协同及临床决策证据生成与融合三种核心方法,并从临床知识库动态更新、病例数据库与模型深度融合、人机协作病例管理及类OpenClaw智能医生助理四个方面,提出未来发展建议,为推动乳腺癌全周期精准诊疗及MDT模式优化提供参考。

本文引用格式

朱能军 , 曹健 , 陈小松 , 朱思吉 . 大语言模型赋能乳腺外科精准决策与全周期病人管理[J]. 外科理论与实践, 2026 , 31(03) : 185 -190 . DOI: 10.16139/j.1007-9610.2026.03.02

Abstract

Early-stage breast cancer diagnosis and treatment are characterized by long disease course, high heterogeneity, multi-source and heterogeneous data, and dynamic evolving decision-making. The traditional multidisciplinary team (MDT) decision-making model faces challenges such as low efficiency and fragmented whole-cycle management. Large language models (LLMs) provide a new approach to solving these problems by virtue of their advantages in processing unstructured text, integrating multi-source data, and assisting clinical reasoning. This paper elaborated on the application value of LLMs in breast cancer MDT decision-making, focused on analyzing three core methods: personalized treatment recommendation agents, multi-agent collaboration, and clinical decision-making evidence generation and fusion. Furthermore, it proposed future development strategies across four dimensions: dynamic update of clinical knowledge bases, in-depth integration of case databases and models, human-machine collaborative case management, and OpenClaw-style intelligent physician assistant, providing references for promoting whole-cycle precise diagnosis and treatment of breast cancer and optimizing the MDT model.

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