Journal of Surgery Concepts & Practice >

2024 , Vol. 29 >Issue 05: 401 - 404

DOI: https://doi.org/10.16139/j.1007-9610.2024.05.06

Consensus and guideline

Hereditary breast cancer risk gene assessment and counseling: interpretation of NCCN guidelines and Ruijin Hospital clinical practice

  • HAN Mengyuan ,
  • CHEN Xiaosong
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  • Department of General Surgery, Comprehensive Breast Health Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

Received date: 2024-01-08

  Online published: 2025-01-23

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Abstract

Hereditary breast cancer-related gene mutations significantly increase the risk of breast cancer in women. In this regard, the National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Genetic/Familial High-Risk Assessment was developed to guide genetic assessment and counseling in mutation carriers of breast cancer risk genes, providing crucial information for the prevention, screening and treatment of breast cancer. This article provided an interpretation of the NCCN Clinical Practice Guidelines in Genetic/Familial High-Risk Assessment, integrating the clinical practice experience of Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.

Key words： Breast cancer; Hereditary risk gene; Gene mutation; NCCN guidelines; Practice

Cite this article

HAN Mengyuan , CHEN Xiaosong . Hereditary breast cancer risk gene assessment and counseling: interpretation of NCCN guidelines and Ruijin Hospital clinical practice[J]. Journal of Surgery Concepts & Practice, 2024 , 29(05) : 401 -404 . DOI: 10.16139/j.1007-9610.2024.05.06

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