Journal of Surgery Concepts & Practice >
Clinical research on the application of flushing strategy during colonoscopy
Received date: 2025-04-29
Online published: 2026-06-23
Objective To investigate the impact of different flushing strategies on procedure time and polyp detection rate(PDR) during colonoscopy. Methods A multicenter prospective controlled study was conducted, enrolling 248 patients who underwent colonoscopy at three hospitals from 2023 August to 2024 January. The patients were assigned to research group and control group randomly. The research group received a thorough flushing strategy during colonoscopy, while the control group received a limited flushing strategy. Clinical data, endoscopic procedure time, and polyp detection results were recorded and compared between the two groups. Results A total of 248 patients were enrolled, with 125 in the research group and 123 in the control group. Baseline characteristics were comparable between the two groups. The research group demonstrated a significantly higher PDR compared to the control group (P<0.01). Among patients with detected polyps, the research group detected more small polyps in the left colon than the control group (P<0.05). Conclusions The flushing strategy during colonoscopy improves PDR and increases the detection of small polyps in the left colon without prolonging the total procedure time.
Key words: Colonoscopy; Bowel preparation; Flushing; Polyp detection rate(PDR); Quality control
ZHANG Yajing , TAO Yifan , PAN Tong , TAO Dingxia , DAI Yancheng , ZHAO Hang . Clinical research on the application of flushing strategy during colonoscopy[J]. Journal of Surgery Concepts & Practice, 2026 , 31(02) : 137 -143 . DOI: 10.16139/j.1007-9610.2026.02.07
| [1] | KAWAMURA T, SEKIGUCHI M, TAKAMARU H, et al. “Endoscopic” adenoma detection rate as a quality indicator of colonoscopy: first report from the J-SCOUT study[J]. Dig Endosc, 2023, 35(5):615-624. |
| [2] | JACOBSON B C, ANDERSON J C, BURKE C A, et al. Optimizing bowel preparation quality for colonoscopy: consensus recommendations by the US multi-society task force on colorectal cancer[J]. Gastroenterology, 2025, 168(4):798-829. |
| [3] | KIM S H, KIM O Z, YOO I K, et al. Second examination of the right colon using narrow-band imaging increases adenoma detection rates in the right colon: a multicenter, randomized controlled trial[J]. J Gastroenterol Hepatol, 2025, 40(7):1667-1674. |
| [4] | TSENG C W, HSIEH Y H, KOO M, et al. Comparing right colon adenoma detection rate during water exchange and air insufflation: a double-blind randomized controlled trial[J]. Tech Coloproctol, 2022, 26(1):35-44. |
| [5] | KALTENBACH T, GAWRON A, MEYER C S, et al. Adenoma detection rate (ADR) irrespective of indication is comparable to screening ADR: implications for quality monitoring[J]. Clin Gastroenterol Hepatol, 2021, 19(9):1883-1889. |
| [6] | ZHAO S, WANG S, PAN P, et al. Magnitude, risk factors, and factors associated with adenoma miss rate of tan-dem colonoscopy: a systematic review and meta- analysis[J]. Gastroenterology, 2019, 156(6):1661-1674. |
| [7] | SHAHINI E, SINAGRA E, VITELLO A, et al. Factors affecting the quality of bowel preparation for colonoscopy in hard-to-prepare patients: evidence from the literature[J]. World J Gastroenterol, 2023, 29(11):1685-1707. |
| [8] | LIU W Q, SHU L, ZHOU X, et al. Evaluation of the efficacy of polyethylene glycol in combination with different doses of linaclotide in a fractionated bowel preparation for colonoscopy: a prospective randomized controlled study[J]. Int J Colorectal Dis, 2024, 39(1):143. |
| [9] | 中华医学会消化内镜学分会结直肠学组. 结肠镜检查肠道准备专家共识意见(2023, 广州)[J]. 中华消化内镜杂志,2023, 40(6):421-430. |
| Colorectal Group, Digestive Endoscopy Branch of Chinese Medical Association. Consensus on bowel preparation for colonoscopy (2023, Guangzhou)[J]. Chin J Dig Endosc,2023, 40(6):421-430. | |
| [10] | KASTENBERG D, BERTIGER G, BROGADIR S. Bowel preparation quality scales for colonoscopy[J]. World J Gastroenterol, 2018, 24(26):2833-2843. |
| [11] | FAVERI M C, SOUZA D, ZUNIGA I, et al. Enhanced instructions for inpatients undergoing colonoscopy: a systematic review and meta-analysis of randomized controlled trials[J]. J Surg Res, 2025,314:229-239. |
| [12] | NIEDERMAIER T, AMITAY E L, GIES A, et al. Impact of inadequate bowel cleansing on colonoscopic findings in routine screening practice[J]. Clin Trans Gastroenterol, 2020, 11(4):e00169. |
| [13] | BHURWAL A, RATTAN P, SARKAR A, et al. A comparison of 9-min colonoscopy withdrawal time and 6-min colonoscopy withdrawal time: a systematic review and meta-analysis[J]. J Gastroenterol Hepatol, 2021, 36(12):3260-3267. |
| [14] | 徐起, 宫爱霞, 张经文, 等. 退镜时间对结肠息肉检出率影响的研究[J]. 中华消化内镜杂志, 2019, 36(12):936-938. |
| XU Q, GONG A X, ZHANG J W, et al. Effect of withdrawal time on colon polyp detection rate[J]. Chin J Dig Endosc, 2019, 36(12):936-938. | |
| [15] | BRONZWAER M E S, GREUTER M J E, BLEIJENBERG A G C, et al. Impact of differences in adenoma and proximal serrated polyp detection rate on the long-term effectiveness of FIT-based colorectal cancer screening[J]. BMC Cancer, 2018, 18(1):465. |
| [16] | PARK S H, HONG K I, PARK H C, et al. Colonic polyp study: differences in adenoma characteristics based on colonoscopy history over 5-year follow-up period[J]. J Clin Med, 2024, 14(1):194. |
| [17] | JUNG Y, CHA J M, LEE N H, et al. Impact of endoscopists' personality traits on adenoma and polyp detection rates in colonoscopy: a kasid multicenter study[J]. Dig Dis Sci, 2020, 65(8):2302-2310. |
| [18] | NG S, SREENIVASAN A K, PECORIELLO J, et al. Polyp detection rate correlates strongly with adenoma detection rate in trainee endoscopists[J]. Dig Dis Sci, 2020, 65(8):2229-2233. |
| [19] | FACCIORUSSO A, BUCCINO V R, TONTI P, et al. Impact of fellow participation on colon adenoma detection rates: a multicenter randomized trial[J]. Gastrointest Endosc, 2020, 92(6):1228-1235. |
| [20] | HASSAN C, SPADACCINI M, IANNONE A, et al. Performance of artificial intelligence in colonoscopy for ade-noma and polyp detection: a systematic review and meta-analysis[J]. Gastrointest Endosc, 2021, 93(1):77-85,e6. |
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