组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2024, Vol. 20 ›› Issue (3): 318-.

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中医外治法对四肢难愈性创面修复的临床疗效研究

  

  • 出版日期:2024-06-01 发布日期:2024-07-05

Clinical study on the effect of traditional Chinese medicine external treatment on the repair refractory wounds in the limbs

  • Online:2024-06-01 Published:2024-07-05

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摘要：

目的　探索中医外治法对四肢难愈性创面修复的临床疗效。方法　将患者按治疗方式分为2组，观察组采用紫归长皮膏联合艾灸的中医外治法，对照组采用生长因子联合凡士林油纱治疗，比较两组患者的临床疗效。结果　共收集病例67例，其中观察组35例，对照组32例。经治疗所有患者创面均愈合，观察组平均愈合时间（43.94±24.92） d，短于对照组的（62.03±64.88） d，但组间差异无统计学意义（P＞0.05）。观察组与对照组愈合时间≤2个月者分别占82.86%、59.38%，差异有统计学意义（P＜0.05）。治疗前观察组与对照组创面平均面积分别为（10.93±14.93） cm2 、（8.13±7.53） cm2 ，治疗后30日，观察组与对照组创面面积分别为（2.61±6.91） cm2 、（2.66±4.34） cm2 。经重复测量方差分析检验，发现随着治疗时间变化，观察组创面缩小的速率显著较快。治疗后观察组疼痛视觉模拟（Visual analogue scale，VAS）评分（0.86±0.91）分，显著低于对照组的（1.25±0.51）分（P＜0.05）。创面愈合 1 个月后，观察组温哥华瘢痕量表（Vancouver scarscale，VSS）评分（3.45±1.82）分，显著低于对照组的（4.81±1.54）分（P＜0.05）。结论中医外治法能缩短四肢难愈性创面的治疗时间，减轻患者疼痛，抑制瘢痕形成。

关键词:

Abstract:

Objective To explore the clinical efficacy of traditional Chinese medicine external treatment for the repair of refractory wounds in the limbs. Methods Patients were divided into two groups according to treatment methods. The observation group received traditional Chinese medicine external treatment with Zigui Zhangpi ointment combined with moxibustion， while the control group received treatment with growth factor combined with vaseline oil gauze. The clinical efficacy of the two groups was retrospectively analyzed. Results A total of 67 cases were collected， including 35 in the observation group and 32 in the control group. After treatment， all the wounds healed， and the average healing time in the observation group was （43.94±24.92） days， shorter than （62.03±64.88） days in the control group， but with no statistically significant difference （P>0.05）. The rate of healing within 2 months were 82.86% and 59.38% in the observation group and control group， respectively， and the difference was statistically significant （P<0.05）. Before treatment， the average wound area of the observation group and the control group were （10.93±14.93） cm2 and （8.13±7.53） cm2 ， respectively. And 30 daysafter treatment， the wound area of the observation group and the control group were （2.61±6.91） cm2 and （2.66±4.34） cm2 ，respectively. It was found that with the change of treatment time， the rate of wound reduction was significantly faster in the
observation group. After treatment， the visual analogue scale （VAS） score of pain in the observation group was 0.86±0.91，
significantly lower than that in the control group （1.25±0.51，P<0.05）.After one month of wound healing， the Vancouver
scar scale （VSS） score of the observation group was 3.45±1.82， significantly lower than that of the control group（4.81±1.54，P<0.05）.Conclusion Traditional Chinese medicine external treatment can shorten the treatment time of refractory wounds in the limbs， reduce the pain of patient， and inhibit scar formation.

Key words:

Retrospective research