组织工程与重建外科杂志 ›› 2025, Vol. 21 ›› Issue (3): 297-.

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3D打印技术在骨组织工程中的应用研究进展

  

  • 出版日期:2025-06-02 发布日期:2025-07-01

Research progress of 3D printing technology in bone tissue engineering

  • Online:2025-06-02 Published:2025-07-01

摘要: 近年来,3D打印技术在医学领域得到广泛应用,特别是在骨组织工程方面。3D打印技术能够将不同类型的活 体细胞整合到传统微观或纳米级生物材料构成的三维结构中,从而创建出能够再生受损组织的人工骨植入物。该技术 可根据患者的具体需求定制骨植入物的外形和尺寸,并调整材料的力学特性和孔隙结构,以促进细胞附着、增殖和骨组 织再生。这种个性化的治疗方法可为患者提供更好的治疗效果和功能恢复。本综述介绍了几种常用的3D打印方法, 以及用于骨替代物的3D打印材料,并重点讨论了在骨修复和再生方面的技术应用。

关键词: 3D打印, &emsp, 人工骨, &emsp, 骨组织工程, &emsp, 骨修复

Abstract:  In recent years, 3D printing technology has been widely applied in the field of medicine, especially in the area of bone tissue engineering. 3D printing technology is capable of integrating different types of living cells into threedimensional structures composed of traditional micro- or nano-scale biomaterials, thereby creating artificial bone implants capable of regenerating damaged tissues. This technology enables the customization of the shape and size of bone implants according to the specific needs of patients, as well as the adjustment of material mechanical properties and pore structures to promote cell attachment, proliferation, and bone tissue regeneration. Such personalized treatment methods can provide patients with improved therapeutic effects and functional recovery. This review introduced several commonly used 3D printing methods and materials for bone substitutes, with a particular focus on their technical applications in bone repair and regeneration, aiming to familiarize readers with the latest developments and prospects of this technology in the field of bone tissue engineering.

Key words: 3D printing, &emsp, Artificial bone, &emsp, Bone tissue engineering, &emsp, Bone repair