目的应用3D成像系统分析A型肉毒毒素联合透明质酸注射隆鼻的效果。方法根据双盲随机分组原则将40例隆鼻患者分为对照组和观察组,每组20例。对照组采用单纯透明质酸注射隆鼻,观察组采用A型肉毒毒素联合透明质酸注射隆鼻,使用3D图像记录两组患者透明质酸注射物的吸收率,比较两组隆鼻术后材料吸收率、术后效果及并发症发生率。结果观察组注射后6个月、12个月材料吸收率低于对照组(P<0.05);两组患者的鼻外形满意度及并发症发生率均无明显统计学差异(P>0.05)。结论相比单纯透明质酸注射隆鼻,A型肉毒毒素联合透明质酸注射隆鼻的材料吸收率较低,可维持时间更久。

Objective To explore the efficacy of botulinum toxin A combined with hyaluronic acid for augmentation rhinoplasty analyzed by 3D image system. Methods According to the principle of double-blind randomized grouping, 40 patients received hyaluronic acid rhinoplasty were divided into control group (n=20) and observation group (n=20). Patients in control group were treated with hyaluronic acid injection alone, while patients in observation group were treated with botulinum toxin A combined with hyaluronic acid injection. The absorptivity of hyaluronic acid was recorded by 3D image system. The material absorptivity, effect and incidence of complications after augmentation rhinoplasty in the two groups were statistically analyzed. Results The material absorption rate of the observation group was lower than that of the control group 6 months and 12 months after injection (P<0.05). There was no significant difference in the nasal aesthetic satisfaction and incidence of complications between the two groups (P>0.05). Conclusion Botulinum toxin A combined with hyaluronic acid injection has lower absorption rate and longer duration than hyaluronic acid injection alone.