皮肤创伤愈合和增生性瘢痕一直是临床试图攻克的难点,已建立了多种实验动物模型用于该领域的实验研究。但是,由于动物与人在皮肤结构上差异较大,选择理想的动物模型极为困难。本文就目前常用的皮肤创伤愈合和增生性瘢痕动物模型的研究进展进行综述。

Cutaneous wound healing and hypertrophic scar are both the research hotspots in plastic surgery. There are a number of animal models for research. However, phylogenetic variation of skin structure between human and other animals hinders the development of optimal animal model. In this paper, the advancement of animal models for cutaneous wound healing and hypertrophic scar was reviewed.