目的 探讨动态增强核磁共振在保乳手术中的应用价值。方法 选取42例行保乳手术的早期乳腺癌患者,结合病理资料评价手术切缘和前哨淋巴结数目情况,比较分析乳腺动态增强核磁共振与乳腺多普勒超声在保乳手术中的应用效果。结果 乳腺动态增强核磁共振检查的形态学准确率和术前评估有效率明显优于乳腺彩色多普勒检查结果;在首次手术切缘阴性率、肿瘤切除最小范围判定率,以及前哨淋巴结数目检出率上也明显优于乳腺多普勒超声检查结果(P<0.05)。乳腺动态增强核磁共振检查评估的肿瘤大小几乎类同于病理检测结果 (P>0.05)。结论 乳腺动态增强核磁共振检查在保乳手术患者的术前评估上有优势,其安全性、可行性佳,值得临床推广应用。

Objective To evaluate the role of dynamic contrast-enhanced magnetic resonance in the breast-conserving operation for early breast cancer.Methods Clinical data of 42 patients with early breast cancer were retrospectively analyzed.Pathological diagnosis was used to estimate the surgical margin or number of sentinel node.The effect of breast dynamic contrast-enhanced magnetic resonance and breast doppler ultrasonography in the breast conserving operation was analyzed and compared.Results The morphological accuracy and efficiency of preoperative evaluation in the doppler ultrasonography was lower than that in the dynamic contrast-enhanced magnetic resonance(P<0.05);The primary negative margin rate,determine rate of minimally extent and sentinel node dissection rate of the oncological excision in the dynamic contrast-enhanced magnetic resonance was better than those in the doppler ultrasonography(P<0.05).There was no significant difference between the breast dynamic contrast-enhanced magnetic resonance and pathological examination in the evaluation of tumor size(P>0.05).Conclusion The breast dynamic contrast-enhanced magnetic resonance has advantages in preoperative evaluation of breast conserving operation with good safety and feasibility,and is worthy of clinical promotion.