瘢痕疙瘩是一种结缔组织过度增生的皮肤疾病,其发生可能与遗传、局部张力以及免疫内分泌有关,但瘢痕疙瘩确切的发病机制尚未阐明,没有对应的高效治疗方案,目前主要根据临床表现进行综合性治疗,以期获得最佳疗效。本文对近几年来瘢痕疙瘩的治疗方法和发病机制等的相关研究进展进行综述。

Keloid is a kind of dermatosis with connective tissue hyperplasia.Several etiological factors for keloids have been proposed in the past,including genetic predisposition,tension present in the local skin environment and immunoendocrinology factors.However,the pathogenesis of keloid has not been elucidated,and there is no appropriate treatment to get the satisfactory therapeutic effect.At present,comprehensive treatment based on clinical manifestations is mainly applicated to obtain the best therapeutic effect.In this paper,the progress of clinical therapy and pathogenesis of keloids in recent years were reviewed.