穿支皮瓣是创伤修复的研究热点,穿支皮瓣研究的重点和难点则在于choke vessels。我们对近年来choke vessels扩展研究的相关文献进行综述,目前的研究主要聚焦于形态学的描述,其扩张机制很可能是剪切力变化,激活TRPV4,通过NF-kb通路而导致choke vessels扩张。

The perforator flap has become a research focus in plastic and reconstructive surgery, and choke vessels is the emphasis and difficulty in the study of perforator flap. In this paper, the recently published literature at home and abroad about the choke vessels dilation was reviewed and summarized. The research of choke vessels is mainly about the morphology, and chemical activation of TRPV4 as a therapeutic target may promote the dilation of choke vessels.