目的 探索剥脱性激光治疗儿童眼睑及眼周先天性黑色素痣的疗效。方法 2014年1月至2016年12月,22例眼睑及眼周先天性黑色素痣患儿接受剥脱性激光治疗,采用超脉冲CO2激光或铒激光,治疗间隔1个月,随访6个月以上。依据治疗前后的照片,统计病灶清除率(5级)。结果 22名患儿平均治疗7.4次,平均随访23个月。9例疗效差,4例疗效一般,5例疗效较好,2例疗效极好,2例病灶清除,总有效率为41%。3例患者出现色素脱失。结论 剥脱性激光治疗儿童眼睑及眼周黑色素痣是安全有效的。

Objective To explore the efficacy of ablative lasers in treating children's congenital melanocytic nevi of eyelids and periorbital areas. Methods From January 2014 to December 2016, 22 children received ablative laser therapies, including carbon dioxide laser or Er:bium laser. The interval duration was at least 1 month and the follow-up time was at least 6 months. Results were graded as percent clearance in five grades according to the pre-operative and post-operative photographs. Results All 22 patients received mean 7.4 laser treatment sessions with a mean follow-up of 23 months. Among the 22 patients, the poor, fair, good, excellent and clearance ones were 9, 4, 5, 2 and 2, respectively, and the effective rate was 41%. Dyspigmentation was observed in 3 cases. Conclusion Using ablative lasers to treat congenital melanocytic nevi of eyelids and periorbital areas is safe and effective.