无水乙醇血管内治疗是目前针对颅外脉管畸形最有效的治疗方法,心肺衰竭是其最严重的致死性并发症,也是阻碍该技术开展的重要原因。目前,对于该技术导致的心肺衰竭的临床特点及发生机制尚存争议。我们回顾现有文献中涉及的可能的发生机制,如肺动脉高压、肺血栓、心脏抑制等,关注其发病特点、发生时机、无水乙醇用量、发生预测、预防措施等焦点问题,对上述内容进行系统性综述。

Intravascular administration of absolute ethanol is the most effective treatment for vascular malformation. However, catastrophic cardiovascular collapse, although rare but fatal, may occurred during the procedure. At present, the clinical characteristics and pathogenesis of this fatal complication are still controversial. Vital aspects which may involved in the pathogenesis: pulmonary hypertension, pulmonary embolism, cardiac depression were reviewed. And the clinical characteristics of the reported cases, focusing on the timing, the dosage of ethanol, prediction and prevention were also reviewed systematically.