目的 评价A型肉毒毒素在治疗咬肌肥大中的作用。方法 2005年8月至2014年1月,对15例咬肌肥大患者行A型肉毒毒素治疗,并应用B型超声于术前和术后4、12、24周测量咬肌厚度。结果 本组患者术后随访6个月,咬肌注射A型肉毒毒素后4、12、24周,咬肌厚度萎缩(15.60±4.96)%、(27.72±9.13)%和(24.32±8.86)%。结论 A型肉毒毒素能有效减少咬肌厚度;B型超声测量能有效地反映咬肌萎缩的程度。

Objective To evaluate the effect of botulinum toxin type Ain the treatment of masseteric hypertrophy.Methods From August 2005 to January 2014,15 women with masseteric hypertrophy were enrolled in this study.Fifty units of botulinum tosin type A was injected bilaterally in the masseter muscles .The thickness of masseter muscles was measured preoperatively,4,12 and 24 weeks postoperatively using B-ultrasound .Results All the patients were followed up for 6 months.The mean reduction of masseter muscle thickness were （15.60±4.96%）at 4 weeks and （27.72±9.13）%at 12 weeks postoperatively.The percent of reduction decreased to （24.32±8.86）%at 24 weeks postoperativelyl.Conclusion Botulinum toxin type Ais effective in treating hypertrophy of the masster muscle .B-ultrasound could effectively reflect the reduction of muscle thickness after botulinum toxin type A injection.