目的 探讨应用自体脂肪颗粒移植改善鼻唇沟凹陷的效果。方法 2011年11月至2014年12月,利用自体脂肪颗粒注射填充鼻唇沟凹陷91例。选取腰腹部或大腿作为脂肪供区,利用负压吸脂机获取脂肪颗粒,吸水浓缩法纯化后,多层次、多隧道、多点少量注射填充91例患者的鼻唇沟凹陷。结果 术后随访6~36个月,56例患者一次注射填充即达满意效果,35例患者经过两次注射填充达到满意效果。每侧注射量1.2~4.6 m L。本组患者均无严重并发症。结论自体脂肪颗粒移植注射填充鼻唇沟凹陷,效果优良,并发症少,值得临床推广应用。

Objective To investigate the clinical application of autologous fat granules injection for nasolabial groove depression. Methods From November 2011 to December 2014, 91 cases with nasolabial groove depression were treated by autologous fat granules injection. The fat granule was harvested by liposuction from waist abdomen or lateral thigh under intravenous anesthesia and local infiltration anesthesia. After purified, the fat was injected into the nasolabial groove by multiple-layers, multiple-tunnels, multiple-points and low-amounts technique. Results After followed up for 6 to 36 months, 56 cases achieved the expected effect by injecting once and 35 cases achieved satisfactory results after reoperation.The amount of autologous fat for each side was 1.2 ml to 4.6 ml. No severe complication was observed. Conclusion Autologous fat granules injection for nasolabial groove depression is effective with few complication, and is worthy of clinical application.