应力改变介导的细胞凋亡与许多疾病的发生、发展密切相关,研究该机制可为相关疾病提供预防、治疗的方法。本文就细胞凋亡的基本特点、应力介导细胞凋亡的相关研究、应力模型的建立及凋亡检测的方法等方面进行综述。

Mechanical stress-induced apoptosis,as programmed cell death,is often correlated with many diseases.Research of mechanical stress-induced apoptosis could provide the prevention and therapy of relative diseases.In this review,the basic features of apoptosis,relative research of stress-induced apoptosis,the establishment of the strain model and the methods of cell apoptosis detection are all reviewed.The research direction of stress-induced apoptosis is also proposed.