组织工程与重建外科杂志

组织工程与重建外科杂志 >

2008 , Vol. 4 >Issue 6: 301 - 304

DOI: https://doi.org/10.3969/j.issn.1673-0364.2008.06.001

论著

多孔钙磷陶瓷表面浸涂制备明胶/HA复合涂层

展开
  • 东南大学材料科学与工程学院;河海大学材料科学与工程学院;

网络出版日期: 2020-07-23

收起

Preparation of Hydroxyapatite/gelatin Composite Coating on Porous Calcium Phosphate Ceramic by Dipping Method

Expand
  • 1 School of Materials Science and Engineering;Southeast University;Nanjing 210096;China;2 School of Materials Science and Engineering;Hehai University;Nanjing 210098;China.;

Online published: 2020-07-23

Fold

摘要

目的采用有机泡沫浸渍法制备β-磷酸三钙(β-TCP)多孔生物陶瓷,以明胶/羟基磷灰石(Hydroxyapatite,HA)复合浆料对其进行表面浸涂处理。本研究旨在保证高孔隙率的前提下提高多孔支架的综合性能。方法利用X-射线衍射仪对β-TCP多孔生物陶瓷进行相组成分析,并研究多孔支架涂覆前后的孔隙率和孔隙特征的变化以及不同明胶/HA比例对支架性能的影响。结果β-TCP多孔生物陶瓷烧结后的主要成分为(Ca,Mg)3(PO4)2和β-Ca2P2O7。涂覆前后多孔支架的孔隙率并没有发生明显改变,但涂覆处理后表面粗糙度明显增大,涂层与支架具有良好的结合界面,涂层中有大量的微孔存在。结论涂覆处理在β-TCP多孔生物陶瓷支架孔隙率基本不变的情况下,成功地在其表面制备出明胶/HA复合涂层,随之形成的粗糙表面形貌,将有利于细胞的早期粘附。

关键词： β-磷酸三钙支架; 羟基磷灰石; 明胶; 复合涂层

本文引用格式

张艳，董寅生，刘斌，林萍华，储成林，盛晓波，郭超 . 多孔钙磷陶瓷表面浸涂制备明胶/HA复合涂层[J]. 组织工程与重建外科杂志, 2008 , 4(6) : 301 -304 . DOI: 10.3969/j.issn.1673-0364.2008.06.001

Abstract

Objective To fabricate porous β-TCP ceramic scaffolds were fabricated by the foam impregnation technology and coated using HA/gelatin composite by dipping in their slurry. The aim of this study is to improve comprehensive properties of the ceramic scaffold. Methods The phase composition, porosity and porous characteristics of the scaffolds before and after coating treatment with different GEL/HA radio were investigated. Results The main composition of the scaffold was composed mainly of (Ca,Mg)3(PO4)2 and β...

Key words： β-TCP scaffold; Hydroxyapatite; Gelatin; Composite coating

Options
文章导航

/

〈 〉