目的 探讨DSA引导下聚多卡醇泡沫硬化剂联合平阳霉素硬化注射,治疗学龄前儿童舌静脉畸形的疗效和安全性。

方法 回顾性分析2017年1月至2018年12月接受硬化治疗的26例舌静脉畸形的学龄前患儿资料。术中多角度穿刺舌体病灶,回抽见血后用注射器注射造影剂进行DSA造影,并在DSA透视下注射聚多卡醇泡沫硬化剂或平阳霉素进行治疗。详细记录患儿一般资料、临床表现、影像资料、治疗效果及并发症情况。

结果 26例患儿共进行72次硬化治疗,平均2.77次/例(1~4次/例)。所有患儿临床症状均有不同程度缓解,其中治愈4例、基本缓解20例、有效2例,总体有效率100%。有23例患儿出现轻度舌体肿胀,4例患儿出现术后发热,26例患儿均未见严重并发症。

结论 聚多卡醇泡沫硬化剂联合平阳霉素注射治疗学龄前儿童舌静脉畸形,安全有效,并发症较轻微,值得临床推广应用。

Objective To evaluate the clinical efficacy and safety of sclerotherapy using polidocanol injectable foam combined with pinyangmycin in the treatment of venous malformation in tongue of preschoolers.

Methods From January 2017 to December 2018, 26 preschoolers with venous malformation in tongue treated with sclerotherapy were retrospectively analyzed. Intraoperatively, the tongue lesions were punctured from multiple angles, and after the blood was recovered, contrast agent was injected for DSA angiography, and polidocanol injectable foam or pingyangmycin was injected under DSA fluoroscopy. The general information, clinical manifestations, imaging data, therapeutic effect and complications were all recorded.

Results A total of 72 sclerosing treatments were performed in 26 patients, with an average of 2.77 sclerosing treatments per patient (1-4 sclerosing treatments per patient). The clinical symptoms of all the children were relieved to different degrees, among which 4 cases were cured, 20 cases were basically relieved, and 2 cases were effective, with an overall effective rate of 100%. Short-term complications included mild swelling (23 cases) and fever (4 cases). No serious complications was observed in the 26 cases.

Conclusion Sclerotherapy using polidocanol injectable foam combined with pinyangmycin is an effective and safe method with few side effect for the treatment of venous malformations in tongue of preschoolers, and is worthy of clinical promotion.