Journal of Tissue Engineering and Reconstructive Surgery ›› 2011, Vol. 7 ›› Issue (1): 48-50.doi: 10.3969/j.issn.1673-0364.2011.01.014

• Original article • Previous Articles     Next Articles

Epigenetic Reprogramming of Nuclei Using Cell Extract

TANG Xinjie,XIE Feng,ZHANG Qun   

  1. Department of Plastic and Reconstructive Surgery,Shanghai Ninth People′s Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200011,China.
  • Published:2020-07-23
  • Contact: 国家自然科学基金  (30900308)

Abstract: Epigenetic reprogramming of nuclei using cell extract becomes popular in recent years.This method indicates that recipient cells receiving transduction of cell extract from donor cells can generate changes of morphology,gene expression and function directing donor cells.It is reported to be used between somatic cells and somatic cells or stem cells as an effective method with no ethical controversy.The current situation,relevant mechanisms and defects concerning reprogramming of cell extract were reviewed.

Key words: Cell extract, Reprogramming, Induction

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