针对工业管道应力分析领域的关键技术需求，以国产化智能管道应力分析软件Start-Prof为研究对象，通过对比国际主流软件CAESARⅡ的工程应用表现，系统验证其技术可靠性与工程适用性。研究以典型管道系统（海水、原油）为例，建立多工况有限元模型，重点考察内压、温度、地震及风载等复合载荷作用下的应力响应特性。结果表明：Start-Prof计算精度与CAESARⅡ保持趋势一致性，二次应力的校核更为保守，所有工况应力比均控制在规范限值内，位移与模态分析结果误差小于2%，研究结果可为后续国产化软件Start-Prof在工程中推广应用提供有力保障。

This paper addresses the critical technical requirements in the field of industrial piping stress analysis by conducting a systematic evaluation of the domestically developed intelligent piping stress analysis software Start-Prof， with comparative studies against the international mainstream software CAESARⅡto verify its technical reliability and engineering applicability. Representative piping systems (seawater， crude oil) were selected as case studies， where finite element models under multiple operating conditions were established to investigate stress response characteristics under combined loads including internal pressure， thermal effects， seismic actions， and wind loads. The results demonstrate that Start-Prof maintains consistent trend accuracy with CAESARⅡ，adopts a more conservative approach in secondary stress evaluation， maintains all stress ratios within code limits， and achieves less than 2% deviation in displacement and modal analysis results. These findings provide strong technical support for the subsequent engineering application and promotion of the domestic Start-Prof software.