In view of the current lack of research on the structural safety of wind-fishery integrated jacket structures for deep offshore applications at water depths of 50 m and above， this study aims to investigate the structural reliability of a 50 m-depth wind-fishery integrated jacket under the combined action of netting loads and flow-blocking devices， so as to provide theoretical support and engineering design references for deep-sea aquaculture demonstration projects and the large-scale development of the wind-fishery integration industry. A combined approach of theoretical analysis and numerical simulation is adopted. Structural conceptual design and load analysis are carried out based on the principles of classical mechanics and structural mechanics. An integrated coupled finite element model involving pile-soil-netting-flow-blocking devices is established using finite element analysis software， and three working conditions are designed， namely without netting， with netting， and with netting plus a 15° baffle plate. A comparative analysis is conducted on the structural dynamic responses under two sea states， i.e.， the 50-year return period storm and normal operation， and ultimate strength verification as well as sensitivity analysis of key parameters is performed. The results show that the additional load of netting has a significant influence on the structural safety of the wind-fishery integrated jacket. Under the 50-year return period storm condition， netting leads to an increase of more than 416% in the maximum stress of key components， the horizontal displacement of the platform， and the maximum internal force of diagonal braces， and the structural fatigue damage degree is also greatly increased. The installation of a 15° baffle plate can effectively optimize the structural stress state， reducing the flow velocity in the netting zone by 23.3%， decreasing the stress of key components and platform displacement by approximately 35%， and lowering the fatigue damage by 82.3%.Meanwhile， the additional load of the baffle plate itself does not cause structural stress to exceed the limit. The sensitivity analysis reveals that the netting damage rate is negatively correlated with structural stress， and 15° is the optimal installation angle of the baffle plate that balances the load reduction effect and its self-load. Optimizing flow-blocking facilities is an effective measure to improve the structural safety of 50 m-depth wind-fishery integrated jackets. Netting should be designed in a coupled manner as an important part of the main structural system， and the integrated coupling analysis method of pile-soil-netting-baffle-jacket should be adopted in the design stage. In future research， water tank model tests （1∶50 scale） and two-way coupled simulations of computational fluid dynamics and structural dynamics will be carried out to accurately capture the load transfer mechanism of netting. In addition， research on modular construction technology of flow-blocking facilities will be conducted to provide more comprehensive technical support for the engineering practice of deep offshore wind-fishery integration projects.