组织工程与重建外科杂志 ›› 2022, Vol. 18 ›› Issue (5): 458-.

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富血小板纤维蛋白在整形外科的应用进展

  

  • 出版日期:2022-10-01 发布日期:2022-11-07

Research progress on clinical applications of platelet-rich fibrin in plastic and reconstructive surgery

  • Online:2022-10-01 Published:2022-11-07

摘要: 富血小板纤维蛋白(Platelet-rich fibrin,PRF)是新一代的血小板浓缩制品,其制备简便,材料完全来源于自身血液,同时富含各种生长因子和细胞因子,对于加快组织修复,促进组织再生有一定作用。虽然PRF受到越来越多的关注,在口腔科、骨科等有了诸多研究报道,但其在整形外科领域的应用仍较少。本文综述近年来相关文献,介绍PRF的制备方法及其衍生物,并对PRF在整形外科中的应用报道进行总结。

关键词: 富血小板纤维蛋白,  富白细胞富血小板纤维蛋白,  改良富血小板纤维蛋白,  可注射富血小板纤维蛋白

Abstract: Platelet-rich fibrin (PRF) is a new generation of platelet concentrates. It is obtained by centrifuging whole blood without any additives. So the production procedure is very simple. It is rich in various growth factors and cytokines, which can accelerate tissue repair and regeneration. PRF has attracted more and more attention. But reported studies are mostly in dentistry and orthopedics. Reports in the plastic and reconstructive field are rare. In order to provide fully understanding for plastic surgeons regarding to PRF, the preparation techniques, derivatives and clinical applications in plastic surgery were reviewed in this paper.

Key words: Platelet-rich fibrin,  Leukocyte- and platelet-rich fibrin,  Advanced platelet-rich fibrin,  Injectable platelet-rich fibrin