In order to study the influence of vortexinduced vibration(VIV) on mineral particles hydraulic transportation in the deepsea mining, EulerEuler twofluid flow model based on particle dynamics and CFD are employed to simulate the liquidsolid twophase flow field in pipe under VIV. Through the analysis of liquidsolid twophase flow field under several VIV conditions, it is found that VIV changes the axial velocity and concentration distribution of particle. The fluctuation phenomenon of the particle axial velocity occurs, the particle concentration distribution varies cyclical and local concentration increase significantly.