In view of the problems of laboratory management in newly established universities, which include that the laboratory experiment management staff is limited, experiment teaching responsibilities are not clear, experimental equipment utilization rate is low, the enthusiasm of the teachers and the students is lack of the initiative, we propose "Claim System" management mode of experimental teaching. Through claiming the laboratory, the teachers can carry out experiment teaching, make research and innovation, guide students to operate in science and technology activities, and change the status quo of the confusion laboratory management. After three years of exploration and practice, the “Claim System” of laboratory management has achieved good results.