Based on actual conditions in universities and investigation of literature, evaluation systems of use efficiency of large-scale equipment are introduced from the aspects of evaluation methods and index systems. Then the advantages and disadvantages of different evaluation methods such as efficiency coefficient method, AHP, fuzzy comprehensive evaluation and RSR are analyzed. The paper also summarizes the practical application of selecting index and personalized evaluation in the index system from Sichuan University and Wuhan University, and provides certain reference basis for the further theoretical study.