专家论坛

呼吸道及肠道微生物菌群与支气管哮喘的发病及治疗

展开
  • 上海交通大学医学院附属瑞金医院呼吸与危重症医学科 上海交通大学医学院呼吸病研究所,上海 200025

收稿日期: 2019-05-01

  网络出版日期: 2019-06-25

本文引用格式

时国朝, 黄春容 . 呼吸道及肠道微生物菌群与支气管哮喘的发病及治疗[J]. 诊断学理论与实践, 2019 , 18(03) : 241 -245 . DOI: 10.16150/j.1671-2870.2019.03.001

参考文献

[1] Croisant S. Epidemiology of asthma: prevalence and burden of disease[J]. Adv Exp Med Biol, 2014, 795:17-29.
[2] Loftus PA, Wise SK. Epidemiology of asthma[J]. Curr Opin Otolaryngol Head Neck Surg, 2016, 24(3):245-249.
[3] van Tilburg Bernardes E, Arrieta MC. Hygiene Hypothesis in Asthma Development: Is Hygiene to Blame?[J]. Arch Med Res, 2017, 48(8):717-726.
[4] McAleer JP, Kolls JK. Contributions of the intestinal microbiome in lung immunity[J]. Eur J Immunol, 2018, 48(1):39-49.
[5] Alnahas S, Hagner S, Raifer H, et al. IL-17 and TNF-α Are Key Mediators of Moraxella catarrhalis Triggered Exacerbation of Allergic Airway Inflammation[J]. Front Immunol, 2017, 8:1562.
[6] Nguyen LD, Viscogliosi E, Delhaes L. The lung mycobiome: an emerging field of the human respiratory microbiome[J]. Front Microbiol, 2015, 6:89.
[7] Simpson JL, Daly J, Baines KJ, et al. Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma[J]. Eur Respir J, 2016, 47(3):792-800.
[8] Abrahamsson TR, Jakobsson HE, Andersson AF, et al. Low gut microbiota diversity in early infancy precedes asthma at school age[J]. Clin Exp Allergy, 2014, 44(6):842-850.
[9] Arrieta MC, Stiemsma LT, Dimitriu PA, et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma[J]. Sci Transl Med, 2015, 7(307):307ra152.
[10] Thorburn AN, McKenzie CI, Shen S, et al. Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites[J]. Nat Commun, 2015, 6:7320.
[11] Furusawa Y, Obata Y, Fukuda S, et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells[J]. Nature, 2013, 504(7480):446-450.
[12] Noverr MC, Noggle RM, Toews GB, et al. Role of antibiotics and fungal microbiota in driving pulmonary allergic responses[J]. Infect Immun, 2004, 72(9):4996-5003.
[13] Kim YG, Udayanga KG, Totsuka N, et al. Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE?[J]. Cell Host Microbe, 2014, 15(1):95-102.
[14] Li X, Leonardi I, Semon A, et al. Response to Fungal Dysbiosis by Gut-Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease[J]. Cell Host Microbe, 2018, 24(6):847-856.
[15] Erb-Downward JR, Thompson DL, Han MK, et al. Analysis of the lung microbiome in the "healthy" smoker and in COPD[J]. PLoS One, 2011, 6(2):e16384.
[16] Huang YJ, Nelson CE, Brodie EL, et al. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma[J]. J Allergy Clin Immunol, 2011, 127(2):372-381,e1-e3.
[17] Li N, Qiu R, Yang Z, et al. Sputum microbiota in severe asthma patients: Relationship to eosinophilic inflammation[J]. Respir Med, 2017, 131:192-198.
[18] Goldman DL, Chen Z, Shankar V, et al. Lower airway microbiota and mycobiota in children with severe asthma[J]. J Allergy Clin Immunol, 2018, 141(2):808-811,e7.
[19] Zhang Q, Cox M, Liang Z, et al. Airway Microbiota in Severe Asthma and Relationship to Asthma Severity and Phenotypes[J]. PLoS One, 2016, 11(4):e0152724.
[20] Huang YJ, Nariya S, Harris JM, et al. The airway microbiome in patients with severe asthma: Associations with disease features and severity[J]. J Allergy Clin Immunol, 2015, 136(4):874-884.
[21] Sverrild A, Kiilerich P, Brejnrod A, et al. Eosinophilic airway inflammation in asthmatic patients is associated with an altered airway microbiome[J]. J Allergy Clin Immunol, 2017, 140(2):407-417,e11.
[22] Green BJ, Wiriyachaiporn S, Grainge C, et al. Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma[J]. PLoS One, 2014, 9(6):e100645.
[23] Denner DR, Sangwan N, Becker JB, et al. Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways[J]. J Allergy Clin Immunol, 2016, 137(5):1398-1405,e3.
[24] Durack J, Lynch SV, Nariya S, et al. Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment[J]. J Allergy Clin Immunol, 2017, 140(1):63-75.
[25] Goleva E, Jackson LP, Harris JK, et al. The effects of airway microbiome on corticosteroid responsiveness in asthma[J]. Am J Respir Crit Care Med, 2013, 188(10):1193-1201.
[26] Vientós-Plotts AI, Ericsson AC, Rindt H, et al. Oral Probiotics Alter Healthy Feline Respiratory Microbiota[J]. Front Microbiol, 2017, 8:1287.
[27] Setia A, Bhandari SK, House JD, et al. Development and in vitro evaluation of an Escherichia coli probiotic able to inhibit the growth of pathogenic Escherichia coli K88[J]. J Anim Sci, 2009, 87(6):2005-2012.
[28] Pochard P, Gosset P, Grangette C, et al. Lactic acid bacteria inhibit TH2 cytokine production by mononuclear cells from allergic patients[J]. J Allergy Clin Immunol, 2002, 110(4):617-623.
[29] Hougee S, Vriesema AJ, Wijering SC, et al. Oral treatment with probiotics reduces allergic symptoms in ovalbumin-sensitized mice: a bacterial strain comparative study[J]. Int Arch Allergy Immunol, 2010, 151(2):107-117.
[30] Pascal M, Perez-Gordo M, Caballero T, et al. Microbiome and Allergic Diseases[J]. Front Immunol, 2018, 9:1584.
[31] Durack J, Kimes NE, Lin DL, et al. Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation[J]. Nat Commun, 2018, 9(1):707.
[32] Chen YS, Jan RL, Lin YL, et al. Randomized placebo-controlled trial of lactobacillus on asthmatic children with allergic rhinitis[J]. Pediatr Pulmonol, 2010, 45(11):1111-1120.
[33] van Nimwegen FA, Penders J, Stobberingh EE, et al. Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy[J]. J Allergy Clin Immunol, 2011, 128(5):948-955,e1-e3.
文章导航

/