目的: 探讨老年恶性肿瘤患者住院时的营养状况,分析营养不良与1年内病死率之间的关系。方法: 采用微型营养评定简表(mininutritional assessment-short form,MNA-SF)评估因确诊恶性肿瘤入住瑞金医院老年病科的老年患者的营养状况,同时测定患者体质量指数（body mass index,BMI）、血红蛋白、前白蛋白、白蛋白、三酰甘油、总胆固醇,跟踪随访其1年生存期。结果: 124例患者纳入研究,根据MNA-SF评分,营养正常（86例）、营养不良风险（33例）和营养不良（5例）的检出率分别为69.4%、26.6%和4.0%。所有患者中,总的1年内病死率为17.7%;3组患者中,以营养不良组为最高（3/5）。校正混淆变量后,COX回归模型提示营养不良将增加老年恶性肿瘤患者1年内死亡的风险。结论: 营养不良在一定程度上能够独立预测老年恶性肿瘤患者1年内的死亡风险。
Objectives: To investigate the nutritional status of elderly malignant tumor patients and to analyze the relation between malnutrition and one-year mortality. Methods: The nutritional status of elderly patients diagnosed as malignant tumor admitted in the department of gerontology, Ruijin Hospital were assessed by mininutritional assessment-short form (MNA-SF), and body mass index (BMI), hemoglobin, prealbumin, albumin, triglyceride and total cholesterol were measured and the patients were followed up for calculating the one-year survival. Results: One hundred and twenty four patients were included in the study. The incidence of nutrition, risky malnutrition and malnutrition was 69.4%, 26.6% and 4.0%, respectively, according to the MNA-SF. The one-year mortality was 17.7% in overall patients; and among the three groups, the one-year mortality was the highest(60%) in malnutrition group. After adjustment for confounding variables, COX regression model suggested that malnutrition can increase the risk of one-year mortality. Conclusions: Malnutrition can predict independently the risk of death of the elderly malignant tumor patients within one year.
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