[1] Reynolds HY.Use of bronchoalveolar lavage in humans--past necessity and future imperative[J]. Lung,2000,178(5):271-293.
[2] Mazzone P, Jain P, Arroliga AC, et al. Bronchoscopy and needle biopsy techniques for diagnosis and staging of lung cancer[J]. Clin Chest Med,2002,23(1):137-158,ix.
[3] Govert JA, Kopita JM, Matchar D, et al.Cost-effectiveness of collecting routine cytologic specimens during fiberoptic bronchoscopy for endoscopically visible lung tumor[J]. Chest,1996,109(2):451-456.
[4] Jones AM, Hanson IM, Armstrong GR, et al.Value and accuracy of cytology in addition to histology in the diagnosis of lung cancer at flexible bronchoscopy[J]. Respir Med,2001,95(5):374-378.
[5] Karahalli E, Yilmaz A, Türker H, et al.Usefulness of various diagnostic techniques during fiberoptic bronchoscopy for endoscopically visible lung cancer: should cytologic examinations be performed routinely?[J]. Respiration,2001,68(6):611-614.
[6] Lee HS, Kwon SY, Kim DK, et al.Bronchial washing yield before and after forceps biopsy in patients with endoscopically visible lung cancers[J]. Respirology,2007, 12(2):277-282.
[7] Ost DE, Ernst A, Lei X, et al.Diagnostic Yield and Complications of Bronchoscopy for Peripheral Lung Lesions. Results of the AQuIRE Registry[J]. Am J Respir Crit Care Med,2016,193(1):68-77.
[8] Baaklini WA, Reinoso MA, Gorin AB, et al.Diagnostic yield of fiberoptic bronchoscopy in evaluating solitary pulmonary nodules[J]. Chest,2000,117(4):1049-1054.
[9] Labbé C, Beaudoin S, Martel S, et al. Diagnostic yield of non-guided flexible bronchoscopy for peripheral pulmonary neoplasia[J]. Thorac Cancer,2015 Jul;6(4):517-523.
[10] Rivera MP, Mehta AC, Wahidi MM.Establishing the dia-gnosis of lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines[J]. Chest,2013,143(5 Suppl):e142S-e165S.
[11] Wang Memoli JS, Nietert PJ, Silvestri GA.Meta-analysis of guided bronchoscopy for the evaluation of the pulmonary nodule[J]. Chest,2012,142(2):385-393.
[12] 张新宇. 支气管冲洗液在肺癌患者EGFR基因突变检测中的应用价值[D]. 2018.
[13] da Cunha Santos G, Saieg MA. Preanalytic parameters in epidermal growth factor receptor mutation testing for non-small cell lung carcinoma: A review of cytologic series[J]. Cancer Cytopathol,2015,123(11):633-643.
[14] Mills NE, Fishman CL, Scholes J, et al.Detection of K-ras oncogene mutations in bronchoalveolar lavage fluid for lung cancer diagnosis[J]. J Natl Cancer Inst,1995,87(14):1056-1060.
[15] Allegrini S, Antona J, Mezzapelle R, et al.Epidermal growth factor receptor gene analysis with a highly sensitive molecular assay in routine cytologic specimens of lung adenocarcinoma[J]. Am J Clin Pathol,2012,138(3):377-381.
[16] Kawahara A, Fukumitsu C, Taira T, et al.Epidermal growth factor receptor mutation status in cell-free DNA supernatant of bronchial washings and brushings[J]. Cancer Cytopathol,2015,123(10):620-628.
[17] Park S, Hur JY, Lee KY, et al.Assessment of EGFR mutation status using cell-free DNA from bronchoalveolar lavage fluid[J]. Clin Chem Lab Med,2017,55(10):1489-1495.
[18] Mano H.ALKoma: a cancer subtype with a shared target[J]. Cancer Discov,2012,2(6):495-502.
[19] Soda M, Isobe K, Inoue A, et al.A prospective PCR-based screening for the EML4-ALK oncogene in non-small cell lung cancer[J]. Clin Cancer Res,2012,18(20):5682-5689.
[20] Billah S, Stewart J, Staerkel G, et al.EGFR and KRAS mutations in lung carcinoma: molecular testing by using cytology specimens[J]. Cancer Cytopathol,2011,119(2):111-117.
[21] Leslie C, Giardina T, Carrello A, et al.Detection of EGFR mutational profile by direct dideoxy sequencing in cytology and non-cytology biopsy samples[J]. Pathology,2014,46(4):283-288.
[22] Malentacchi F, Forni G, Vinci S, et al.Quantitative eva-luation of DNA methylation by optimization of a differential-high resolution melt analysis protocol[J]. Nucleic Acids Res,2009,37(12):e86.
[23] Anglim PP, Alonzo TA, Laird-Offringa IA.DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update[J]. Mol Cancer,2008,7:81.
[24] Fahy JV, Wong H, Liu J, et al.Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects[J]. Am J Respir Crit Care Med,1995,152(1):53-58.
[25] Guo M, House MG, Hooker C, et al.Promoter hypermethylation of resected bronchial margins: a field defect of changes?[J]. Clin Cancer Res,2004,10(15):5131-5136.
[26] Millares L, Rosell A, Setó L, et al.Variability in the measurement of the methylation status of lung cancer-related genes in bronchial secretions[J]. Oncol Rep,2014, 32(4):1435-1440.
