新型冠状病毒性肺炎疫情封闭管理期间正念减压疗法对阿尔茨海默病患者情绪障碍及睡眠状况的影响分析
网络出版日期: 2022-02-25
基金资助
国家重点研发计划项目(2018YFC2002300);上海市金山区第六周期医学重点专科建设项目(JSZk2019B06);上海市金山区科学技术创新资金项目(2019-3-24)
Effects of mindfulness-based stress reduction on mood disorders and sleep in patients with Alzheimer′s disease in the context of COVID-19
Online published: 2022-02-25
目的: 探讨因新型冠状病毒性肺炎疫情封闭管理期间基于正念减压疗法(mindfulness-based stress reduction, MBSR)的心理康复干预,对长期住院轻中度阿尔茨海默病(Alzheimer disease,AD)患者情绪障碍及睡眠状况的影响。目的: 入组2020年1月前收治入院的轻中度AD患者70例,所有入选患者均接受为期8周的基于MBSR心理康复干预,干预时间为2020年2月11日至2020年4月30日。在干预开始前,进行患者一般资料收集,并使用汉密尔顿焦虑量表(Hamilton Anxiety Scale,HAMA)、老年抑郁量表(The 15-item Geriatric Depression Scale,GDS-15)及匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index,PSQI)等评估量表对每位入选患者进行初次评估,为期8周的MBSR干预结束时进行再次评估。在初次评估后,对患者一般资料与初次评估结果进行相关性分析。结果: 根据入组轻中度AD患者的焦虑、抑郁程度、睡眠状况评分与其受教育程度呈负相关(r<-0.4;P≤0.01);而患者的睡眠状况评分与其焦虑、抑郁程度呈正相关(r>0.4;P≤0.01)。在接受了8周的MBSR干预后,患者的GDS、HAMA、PSQI评分较初次评估时有明显改善(P<0.05)。结论: 在因疫情封闭管理期间,基于MBSR的心理康复干预有助于改善长期住院轻中度AD患者的焦虑、抑郁等情绪障碍和睡眠状况。
付丛会, 徐英, 苏巍, 文静, 刘志芳, 朱倩, 张静怡, 熊泽民, 陈兰兰, 贾杰 . 新型冠状病毒性肺炎疫情封闭管理期间正念减压疗法对阿尔茨海默病患者情绪障碍及睡眠状况的影响分析[J]. 诊断学理论与实践, 2022 , 21(01) : 46 -51 . DOI: 10.16150/j.1671-2870.2022.01.010
Objective: To investigate the effects of MBSR(mindfulness-based stress reduction)-based mental rehabilitation intervention on mood disorders and sleep status of patients with mild to moderate Alzheimer′s disease (AD) in long-term hospital during closed management of COVID-19 pandemic. Methods: A total of 70 patients with mild to moderate AD who were admitted to hospital before January 2020 were enrolled. All patients received an 8-week psychological rehabilitation intervention based on MBSR from February 11, 2020 to April 30, 2020. Prior to the intervention, general patient data were collected, including Hamilton Anxiety Scale(HAMA), The 15-item Geriatric Depression Scale(GDS-15) and Pittsburgh Sleep Quality Index(PSQI) and other assessment scales were used for initial assessment of each enrolled patient, and re-assessment was performed at the end of the 8-week intervention. After the initial assessment, correlation analysis was conducted between general patient data and the results of the initial assessment in patients. Results: It revealed that anxiety, depression, sleep status of patients were negatively correlated with their education level (R<-0.4; P≤0.01); the sleep status score of patients was positively correlated with the degree of anxiety and depression (R>0.4; P≤0.01); GDS, HAMA and PSQI scores of the patients were significantly improved after 8 weeks of intervention compared with the initial evaluation(P<0.05). Conclusions: Mental rehabilitation intervention based on MBSR during closed management due to COVID-19 can improve anxiety, depression and other mood disorders and sleep status of patients with long-term inpatient mild to moderate AD.
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