收稿日期: 2021-01-18
网络出版日期: 2022-06-28
Analysis of fall risk factors and establishment of risk identification model in elderly stroke patients in Shanghai community
Received date: 2021-01-18
Online published: 2022-06-28
目的:分析在上海社区卫生服务中心随访的老年脑卒中患者的跌倒风险及相关危险因素。 方法:采用便利抽样方法随机选取2019年度在本中心就诊的230例老年脑卒中患者(60~90岁)为研究对象,检测其生化指标,并采用Morse跌倒风险评估量表评估其跌倒风险,根据简易营养评价精法(short-form mini-nutritional assessment,MNA-SF法)将患者分为低风险(≤45分)及高风险组(>45分),采用多因素Logistic回归模型分析跌倒危险因素并构建多因素模型,并用受试者操作特征(receiver operator characteristic,ROC)曲线评价危险因素模型预测老年卒中患者发生跌倒风险的价值。 结果:对跌倒高风险组及跌倒低风险组进行基线分析后,筛选变量进行多因素Logistic回归分析,提示MNA-SF评分[优势比(odd ratio,OR)=0.338,95%置信区间(confidence interval,CI)为0.225~0.508,P<0.001]、血清白蛋白(OR=0.513,95%CI为0.396~0.664,P<0.001)、血红蛋白(OR=0.908,95%CI为0.858~0.961,P=0.001)、女性(OR=4.407,95%CI为1.006~19.311,P=0.049)、高龄(OR=3.464, 95%CI为1.172~10.235,P=0.025)与跌倒相关。其中,女性、高龄(≥80岁)为老年卒中患者跌到的主要危险因素,MNA-SF评分高(≥11分)、血清白蛋白升高为卒中老年患者的主要保护因素,而血红蛋白升高的保护作用较弱。根据以上 5个危险因素构建 ROC 曲线的曲线下面积为 0.925(P<0.05),在预测老年卒中患者跌倒风险中有较高的准确率。 结论:女性、高龄(≥80岁)是老年卒中患者跌倒的危险因素,而血清白蛋白及血红蛋白水平升高、营养状况良好(MNA-SF评分≥11分)则是该人群发生跌倒的保护因素。依据相关危险因素,建立相应的ROC曲线诊断模型,有助于在老年卒中患者中合理、快速地识别跌倒高风险的患者,具有实用价值。
刘安平, 凌枫, 史超, 孙璟 . 上海社区老年脑卒中患者跌倒风险因素分析及风险识别模型的建立[J]. 诊断学理论与实践, 2021 , 20(05) : 475 -479 . DOI: 10.16150/j.1671-2870.2021.05.011
Objective: To investigate the risk for falling, and fall risk related factors by visiting elderly stroke patients in Shanghai Community Health Service Center. Methods: A total of 230 patients aged from 60 to 90 in the Service Center were randomly selected during 2019 using convenience sampling method. Biochemical indicators were detected,and Morse Fall Risk Assessment Scale was used to assess the falling risk of the subjects. According to the short-form mini-nutritional assessment (MNA-SF method), patients were divided into low-risk and high-risk groups. Multivariate Logistic regression model was used to analyze the falling risk factors, and receiver operator characteristic (ROC) curves was used to evaluate the value of risk factors in predicting falling risk in elderly stroke patients. Results: After baseline analysis, Multivariate Logistic regression analysis showed that MNA-SF (OR=0.338, 95%CI: 0.225-0.508, P<0.001), serum albumin(OR=0.513, 95%CI: 0.396-0.664, P<0.001), hemoglobin (OR=0.908, 95%CI: 0.858-0.961, P=0.001), female(OR=4.407, 95%CI: 1.006-19.311, P=0.049), older age(OR=3.464,95%CI: 1.172-10.235, P=0.025) were risk factors for falling in elderly patients. Among these factors, female,older age (≥80 years old) were the risk factors for falling in elderly stroke patients, besides high score of MNA-SF, elevated level of serum albumin were the protection factors, and elevated hemoglobin was less protective. The area under the curve of ROC curve for the model established with 5 risk factors was 0.925 (P<0.05), which has a good performance for predicting falling in elderly stroke patients. Conclusions: It indicates that female, older age (≥80 years old) are the risk factors for falling, while elevated level of serum albumin,hemogolbin, and good nutrition (MNA-SF≥11) are protective factors for falling in elderly stroke patients. Establishment of risk model will help to identify the patients with high risk of falling, which has practical value.
Key words: Elderly people; Stroke; Falling risk; Nutritional status; Risk factor
[1] | Zijlstra GA, van Haastregt JC, van Eijk JT, et al. Prevalence and correlates of fear of falling, and associated avoidance of activity in the general population of community-living older people[J]. Age Ageing, 2007,36(3):304-309. |
[2] | 夏艳. 脑卒中住院患者防跌倒护理的护理体会[J]. 护理研究, 2014(4):351. |
[3] | Lopes KT, Costa DF, Santos LF, et al. Prevalência do medo de cair em uma população de idosos da comunidade e sua correlação com mobilidade, equilíbrio dinamico, risco e histórico de quedas[J]. Rev Bras Fisioter, 2009,13(3):223-229. |
[4] | 任汝静, 殷鹏, 王志会, 等. 中国阿尔茨海默病报告2021[J]. 诊断学理论与实践, 2021,20(4):317-337. |
[5] | Ganz DA, Bao Y, Shekelle PG, et al. Will my patient fall?[J]. JAMA, 2007,297(1):77-86. |
[6] | 中华医学会神经病学分会, 中华医学会神经病学分会脑血管病学组. 中国急性缺血性脑卒中诊治指南2018[J]. 中华神经科杂志, 2018,51(9):666-682. |
[7] | 中国老年保健医学研究会老龄健康服务与标准化分会, 《中国老年保健医学》杂志编辑委员会. 中国老年人跌倒风险评估专家共识(草案)[J]. 中国老年保健医学, 2019,17(4):47-48,50. |
[8] | Abbs E, Brown R, Guzman D, et al. Risk factors for falls in older adults experiencing homelessness: results from the HOPE HOME cohort study[J]. J Gen Intern Med, 2020, 35(6):1813-1820. |
[9] | GR Neri S, S Oliveira J, B Dario A, et al. Does obesity increase the risk and severity of falls in people aged 60 years and older? A systematic review and meta-analysis of observational studies[J]. J Gerontol A Biol Sci Med Sci, 2020,75(5):952-960. |
[10] | 戚晓芳, 刘丽华, 谢淑萍, 等. 肺癌患者在不同放化疗阶段血红蛋白与跌倒风险的相关因素分析[J]. 护士进修杂志, 2018,33(10):921-923. |
[11] | Ferrer A, Badia T, Formiga F, et al. A randomized clinical trial of falls and malnutrition prevention in community-dwelling elders aged 85 years old. The OCTABAIX study[J]. Rev Esp Geriatr Gerontol, 2010,45(2):79-85. |
[12] | Misu S, Asai T, Doi T, et al. Association between gait abnormality and malnutrition in a community-dwelling elderly population[J]. Geriatr Gerontol Int, 2017,17(8):1155-1160. |
[13] | Torres MJ, Féart C, Samieri C, et al. Poor nutritional status is associated with a higher risk of falling and fracture in elderly people living at home in France: the Three-City cohort study[J]. Osteoporos Int, 2015,26(8):2157-2164. |
[14] | Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype[J]. J Gerontol A Biol Sci Med Sci, 2001,56(3):M146-M156. |
[15] | 弓凯, 范存刚. 左旋多巴诱发异动症的相关机制[J]. 国际神经病学神经外科学杂志, 2010,37(5):454-457. |
[16] | 王丽娟, 聂坤, 张玉虎. 血管性帕金森综合征的诊治[J]. 中华神经科杂志, 2021,54(8):833-837. |
[17] | Creaby MW, Cole MH. Gait characteristics and falls in Parkinson′s disease: A systematic review and meta-analysis[J]. Parkinsonism Relat Disord, 2018,57:1-8. |
[18] | 张悦琪, 朱自强, 梅春丽, 等. 脑卒中康复期患者发生跌倒危险因素的meta分析[J]. 中国医药导报, 2020,17(26):108-112. |
[19] | 李宇, 萨丽波, 刘宇翔. 老年综合评估技术在老年高血压合并脑梗死患者跌倒风险分析中的应用[J]. 中国现代医药杂志, 2021,23(5):47-50. |
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