目的： 探讨脂肪肝指数（fatty liver index, FLI）与微量白蛋白尿间的相关性。方法： 于2009年选取上海淞南地区40岁以上的居民4 012人进行横断面调查,采用问卷调查、体格检查等收集相关资料,观察其微量白蛋白尿情况,并计算FLI,分析该人群中FLI与微量白蛋白尿间的相关性。结果： 最终共有3 415人纳入分析,结果提示,随着FLI的升高,不同FLI分组[低FLI组（FLI<30）、中FLI组（30≤FLI<60）和高FLI组（≥60）]中微量白蛋白尿患病率逐渐增加,3组的微量白蛋白尿患病率分别为6.86%、10.99%、15.28%（P<0.000 1）。在校正年龄、性别、吸烟、饮酒、运动、高血压、糖尿病、总胆固醇后,与低FLI组相比,高FLI组人群的微量白蛋白尿患病风险增加了58%（OR=1.58,95%CI为1.17~2.15,P=0.003 2）。在同样的校正因素下,FLI数值每增加10,微量白蛋白尿患病风险增加10%（OR=1.10, 95%CI为1.04~1.15,P=0.000 2）。结论： 上海淞南地区40岁以上人群中,FLI升高与其微量白蛋白尿的患病风险增加相关。

Objective: To investigate the association between fatty liver index (FLI) and prevalence of microalbuminuria. Methods: A cross-sectional survey of 4 012 subjects aged 40 years or older in Songnan Community, Shanghai was conducted in 2009. Questionnaire and anthropometric measurements were collected, and microalbuminuria and the FLI were determined. The association between FLI and microalbuminuria was analyzed. Results: Among the 3 415 subjects in the current analysis, the prevalence of microalbuminuria increased with increase of the FLI. The corresponding prevalence of microalbuminuria were 6.86%, 10.99% and 15.28% in low FLI group(FLI<30), intermediate FLI group(30≤FLI<60) and the high FLI group(FLI≥60), respectively (P<0.000 1). After adjustment for age, sex, smoking status, current drinking, physical activity, systolic blood pressure, diabetes and total cholesterol, the high FLI group was associated with 58% increased risk of microalbuminuria compared with the low FLI group (OR=1.58, 95% CI 1.17-2.15, P=0.003 2). In the same adjusting model,the risk in prevalence of microalbuminuria increased 10% for each 10 unit increase in FLI (OR=1.10, 95% CI 1.04-1.15, P=0.000 2). Conclusions: FLI increas is associated with increased risk of microalbuminuria in subjects aged 40 years or older in Songnan Community, Shanghai.