目的： 分析上海地区胃息肉（gastric polyp, GP）的胃镜检出率及GP的病理特征。方法： 收集2012年12月至2019年5月间在上海交通大学医学院附属瑞金医院北院行胃镜检查者36 857例,统计胃镜GP检出率及相关病理资料。结果： 36 857例行胃镜检查者中有3858例检出GP,检出率为10.47%。≥60岁的患者中,检出GP患者3 858例,检出率为14.75%。与其他年龄组（<30岁、30~39岁、40~49岁、50~59岁）相比,≥60岁患者中息肉直径≥2 cm的构成比较高,为1.8%（P<0.05）,腺瘤性息肉的构成比也较高（1.9%）（P<0.05）,合并上皮内瘤变患者45例,占2.9%,构成比明显较高（P<0.05）,特别是其中3例高级别上皮内瘤变患者年龄均≥60岁。与<60岁的患者相比,≥60岁的GP患者中合并萎缩性胃炎、肠化生者的构成比明显较高,分别为22.4%、34.0%（P均<0.05）;与此相反,存在幽门螺杆菌（Helicobacter pylori,Hp）感染的GP患者中,≥60岁者合并Hp感染的构成比较低（15.1%）,差异有统计学意义（P<0.01）。结论： 相对60岁以下人群而言,≥60岁人群GP检出率较高,为14.75%;与<60岁的GP患者相比,≥60岁GP患者其息肉直径≥2 cm、腺瘤性息肉构成比较高,其合并上皮内瘤变、萎缩性胃炎、肠化生的构成比也较高,故对于≥60岁的患者需更加重视GP的检出及病理检查。

Objective: To explore the detection rate of gastric polyp (GP) in Shanghai and analyze its clinical characteristics. Methods: A total of 36 857 subjects undergone gastroscopy during December 2012 to May 2019 were enrolled, and the detection rate of GP and related pathologic data were analyzed. Results: It revealed that 3 858 patients had GP, with a detection rate of 10.47%. In patients over 60 years old, 1 534 patients were diagnosed as having GP, with a detection rate of 14.75%. Compared with patients in other age groups (<30, 30-39, 40-49, 50-59 years), the constituent ratio of patients with GP diameter ≥2.0 was higher（1.8%）（P<0.05）, so was with adenomatous polyps (1.9%) and with intraepithelial neoplasia (2.9%)（P<0.05). The only three cases with high-grade intraepithelial neoplasia were all ≥60 years old. Besides, the constituent ratio of patients ≥60 years old with atrophic gastritis and with intestinal metaplasia were 22.4% and 34.0%, respectively,which were higher than those of patients <60 years old. In contrast, GP patients ≥60 years old had a lower constituent ratio of Helicobacter pylori infection (15.1%), lower than that of patients under 60 years old (P<0.01). Conclusions: In comparison with the population <60 years old, population ≥60 had a higher detection rate of GP. GP patients of ≥60 years old had higher proportion of polyps diameter greater than 2 cm, adenomatous polyps, intraepithelial neoplasia, atrophic gastritis, and intestinal metaplasia. Therefore, more attention should be paid to the detection and pathology examination of GP in elderly patients.