诊断学理论与实践

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2022 , Vol. 21 >Issue 03: 405 - 407

DOI: https://doi.org/10.16150/j.1671-2870.2022.03.020

病例报告

阴道壁胃肠道外间质瘤一例报道并文献复习

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  • 1.山东第一医科大学附属东阿医院（东阿县人民医院）病理科,山东 252201
    2.山东省第二人民医院病理科,山东 250022

收稿日期: 2021-09-15

  网络出版日期: 2022-08-17

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The extra-gastrointestinal stromal tumors located in vagina: A case report and literature review

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  • 1. Department of Pathology, Dong′e County People′s Hospital, Shandong First Medical University, Shandong 252201, China
    2. Department of Pathology, The Second People′s Hospital of Shandong Province, Shandong 250022, China

Received date: 2021-09-15

  Online published: 2022-08-17

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摘要

胃肠道外间质瘤（extra-gastrointestinal stromal tumor,EGIST）是发生于胃肠道外较少见的间叶组织肿瘤,其与胃肠道间质瘤的免疫表型、组织学形态、基因突变位点及突变频率相似。EGIST患者缺乏典型的临床特征,不易明确诊断,并且由于报道病例较少,尚未有统一的危险度评估标准。本文报道1例原发于阴道壁的EGIST,结合患者的临床资料,采用免疫组化标志物检测得以确诊。复习相关文献后进行综合分析,提示EGIST具有低的发病率,预后较胃肠间质瘤差。

关键词： 胃肠道外间质瘤; 阴道壁; 病理诊断

本文引用格式

郭业兵, 郑金峰 . 阴道壁胃肠道外间质瘤一例报道并文献复习[J]. 诊断学理论与实践, 2022 , 21(03) : 405 -407 . DOI: 10.16150/j.1671-2870.2022.03.020

Abstract

Extra-gastrointestinal stromal tumor(EGIST) is a relatively rare mesenchymal tumor occurring outside the gastrointestinal tract. The immunophenotype, histological morphology, gene mutation sites and mutation frequency of EGIST are similar to GIST. EGIST lacks typical clinical features and is not easily diagnosed. Due to the small number of reported cases, there is no unified risk assessment standard. A case of EGIST originating in vaginal wall is reported in this paper, which diagnosis depended on clinical data and immunohistochemical markers. Literature reviewing suggestes that the incidence of EGIST is low and patients with EGIST have worse prognosis.

Key words： Extra-gastrointestinal stromal tumor; Vaginal wall; Pathologic diagnosis

参考文献

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