[1] 王启晗, 张中文, 吴健, 等. 上海地区胆囊结石病的流行病学调查[J]. 外科理论与实践,2018,23(3):252-257.
[2] Rebholz C, Krawczyk M, Lammert F.Genetics of gallstone disease[J]. Eur J Clin invest,2018,48(7):e12935.
[3] 蒋兆彦, 胡海, 韩天权, 等. 胆固醇的肠肝循环:肝脏和小肠在胆石形成中的作用[J]. 外科理论与实践,2017, 22(3):191-194.
[4] Katsika D, Grjibovski A, Einarsson C, et al.Genetic and environmental influences on symptomatic gallstone di-sease: a Swedish study of 43,141 twin pairs[J]. Hepato-logy,2005,41(5):1138-1143.
[5] Lammert F, Carey MC, Paigen B, et al.Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map[J]. Gastroenterology,2001,120(1):221-238.
[6] Grünhage F, Acalovschi M, Tirziu S, et al.Increased gallstone risk in humans conferred by common variant of hepatic ATP-binding cassette transporter for cholesterol[J]. Hepatology,2007,46(3):793-801.
[7] Lauridsen BK, Stender S, Tybjærg-Hansen A.Genetic variation in NPC1L1 and risk of gallstone disease[J]. J Am Coll Cardiol,2015,66(9):1086.
[8] Tilg H, Moschen AR.Microbiota and diabetes: an evol-ving relationship[J]. Gut,2014,63(9):1513-1521.
[9] Ridaura VK, Faith JJ, Rey FE, et al.Gut microbiota from twins discordant for obesity modulate metabolism in mice[J]. Science,2013,341(6150):1241214.
[10] Henao-Mejia J, Elinav E, Jin C, et al.Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity[J]. Nature,2012,482(7384):179-185.
[11] Canfora EE, Jocken JW, Blaak EE.Short-chain fatty acids in control of body weight and insulin sensitivity[J]. Nat Rev Endocrinol,2015,11(10):577-591.
[12] Frey C, Thorpe C, Abrams G.Gallstone formation in the germ-free mouse[J]. Am J Surg,1968,115(1):75-81.
[13] Fremont-Rahl JJ, Ge Z, Umana C, et al.An analysis of the role of the indigenous microbiota in cholesterol gallstone pathogenesis[J]. PLoS One,2013,8(7):e70657.
[14] Wang Q, Jiao L, He C, et al.Alteration of gut microbiota in association with cholesterol gallstone formation in mice[J]. BMC Gastroenterol,2017,17(1):74.
[15] Kurdi P, Kawanishi K, Mizutani K, et al.Mechanism of growth inhibition by free bile acids in lactobacilli and bifidobacteria[J]. J Bacteriol,2006,188(5):1979-1986.
[16] Islam KB, Fukiya S, Hagio M, et al.Bile acid is a host factor that regulates the composition of the cecal microbiota in rats[J]. Gastroenterology,2011,141(5):1773-1781.
[17] Sayin SI, Wahlström A, Felin J, et al.Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist[J]. Cell Metab,2013,17(2):225-235.
[18] Hu X, Bonde Y, Eggertsen G, et al.Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism[J]. J Intern Med,2014,275(1):27-38.
[19] Wahlström A, Kovatcheva-Datchary P, Ståhlman M, et al.Induction of farnesoid X receptor signaling in germ-free mice colonized with a human microbiota[J]. J Lipid Res,2017,58(2):412-419.
[20] Degirolamo C, Rainaldi S, Bovenga F, et al.Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice[J]. Cell Rep,2014,7(1):12-18.
[21] Gregory JC, Buffa JA, Org E, et al.Transmission of atherosclerosis susceptibility with gut microbial transplantation[J]. J Biol Chem,2015,290(9):5647-5660.
[22] Zhao L, Zhang F, Ding X, et al.Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes[J]. Science,2018,359(6380):1151-1156.
[23] Chu H, Duan Y, Yang L, et al.Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease[J]. Gut,2019,68(2):359-370.
[24] Hoyles L, Fernández-Real JM, Federici M, et al.Mole-cular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women[J]. Nat Med,2018,24(7):1070-1080.
[25] Koeth RA, Wang Z, Levison BS, et al.Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis[J]. Nat Med,2013,19(5):576-585.
[26] Wang Z, Klipfell E, Bennett BJ, et al.Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease[J]. Nature,2011,472(7341):57-63.
[27] Garidou L, Pomié C, Klopp P, et al.The gut microbiota regulates intestinal CD4 T cells expressing RORγt and controls metabolic disease[J]. Cell Metab,2015,22(1):100-112.
[28] Tedesco D, Thapa M, Chin CY, et al.Alterations in intestinal microbiota lead to production of interleukin 17 by intrahepatic γδ T-cell receptor-positive cells and pathogenesis of cholestatic liver disease[J]. Gastroentero-logy,2018,154(8):2178-2193.
[29] Maurer KJ, Rao VP, Ge Z, et al.T-cell function is critical for murine cholesterol gallstone formation[J]. Gastroenterology,2007,133(4):1304-1315.
