目的： 研究腹腔镜胰十二指肠切除术在老年病人的围术期手术疗效,评价安全性及可行性。方法： 回顾性分析自2015年1月至2018年1月在我院普外科完成腹腔镜胰十二指肠切除术病人的临床资料。分为老年组（≥70岁组）和对照组（<70岁组）。比较两组一般资料以及围术期手术学疗效。结果： 82例病人中,男46例,女36例,平均年龄（64.6±10.7）岁,老年组27例,对照组55例。老年组平均手术时间（368±75） min,中位术中出血量200（100~400） mL,中位术后住院时间12（10~21） d。对照组平均手术时间（363±82） min,中位术中出血量100（100~200） mL,中位术后住院时间11.5（10~16） d。两组数据差异无统计学意义。两组术后90 d内死亡率差异无统计学意义,但老年组术后严重并发症总发生率（40.7%）高于对照组（20.0%）（P=0.05）。结论： 腹腔镜胰十二指肠切除术在老年病人中可行。由于老年病人术后并发症发生率高于普通病人,因此,实施时仍需十分谨慎。

Objective To evaluate the feasibility of laparoscopic pancreaticoduodenectomy in elderly patients with peri-operative short-term outcomes and safety. Methods Retrospectively analysis was done with the clinical data of patients who underwent laparoscopic pancreaticoduodenectomy in our department from January 2015 to January 2018. Patients were divided into elderly group (ages 70 years and old) and control group (ages less than 70 years) to compare baseline characteristics and perioperative outcomes between two groups. Results Totally 82 patients were included in this study with 46 male and 36 female and mean age (64.6±10.7) years. There were 27 patients in elderly group and 55 patients in control group. Mean operative time was (368±75) min in elderly group with median blood loss 200 (100-400) mL and median postoperative length of hospital stay 12.0 (10-21)d. In control group, mean operation time was (363±82) min with median blood loss 100 (100-200) mL and median postoperative length of hospital stay 11.5 (10-16) d. There was no statistics difference between two groups. Postoperative 90-day mortality rate was not different statistically between two groups patients. However, higher postoperative morbidity rate was found in elderly group patients (40.7%) more than that in control group patients (20.0%) (P=0.05). Conclusions Laparoscopic pancreaticoduodenectomy was feasible in elderly patients. Relatively higher postoperative morbidity rate of elderly patients should be cautioned when laparoscopic pancreaticoduodenectomy was performed in elderly patients.