综述

胆囊腺肌症的发病机制及诊治研究进展

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  • 1.浙江中医药大学第一临床医学院,浙江 杭州 310053
    2.浙江中医药大学附属第一医院肝胆外科,浙江 杭州 310053

收稿日期: 2021-04-01

  网络出版日期: 2022-03-17

Progress of study on gallbladder adenomyomatosis: pathogenesis, diagnosis and treatment

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  • 1. The First Clinical Medical College of Zhejiang Chinese Medical University, Zhejiang Hangzhou 310053, China
    2. Department of Hepatological Surgery, The First Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang Hangzhou 310053, China

Received date: 2021-04-01

  Online published: 2022-03-17

摘要

胆囊腺肌症(gallbladder adenomyomatosis,GA)是一种临床上较少见、病因及发病机制不明的良性疾病。随着影像检测技术的发展,其诊断有进一步提高。部分学者认为GA与胆囊癌的形成有关,但尚存争议。GA的治疗,有主张胆囊切除,以预防其恶变,也有学者认为部分GA可行随访。目前尚无共识。本文对GA的病因、发病机制和诊治进展进行综述。

本文引用格式

陈炫武, 杨传玉, 蒋敏杰 , 杜卫东 . 胆囊腺肌症的发病机制及诊治研究进展[J]. 外科理论与实践, 2022 , 27(01) : 87 -90 . DOI: 10.16139/j.1007-9610.2022.01.020

Abstract

Gallbladder adenomyomatosis(GA) is a relatively rare benign disease of unknown both etiology and pathogenesis. The development of imaging technology improved diagnosis of GA. Some believed that GA related to gallbladder cancer, which is still controversial. Preventive cholecystectomy was proposed to treat GA and some GA could be followed up. Therefore no consensus of treatment of GA is present now. Etiology, pathogenesis, diagnosis and treatment of GA were included in this article.

参考文献

[1] Jutras JA. Hyperplastic cholecystoses;Hickey lecture,1960[J]. Am J Roentgenol Radium Ther Nucl Med, 1960, 83:795-827.
[2] Mahajan A, Sripathi S. Gallbladder adenomyomatosis mimicking carcinoma: a diagnostic dilemma[J]. J Glob Oncol, 2016, 2(5):341-345.
[3] Keisuke E, Tatsuki M, Yugo T, et al. Adenomyomatosis of the gallbladder with pancreaticobiliary maljunction in a child[J]. J Pediatr Gastroentrol Nutr, 2018, 67(4):e82.
[4] Parolini F, Indolfi G, Magne MG, et al. Adenomyomatosis of the gallbladder in childhood: a systematic review of the literature and an additional case report[J]. World J Clin Pediatr, 2016, 5(2):223-227.
[5] Chen CB, Nasser KM. Gallbladder Adenomyomatosis in an Infant[J]. ACG Case Rep J, 2020, 7(7):e00433.
[6] Eroğlu N, Erduran E, Imamoğlu M, et al. Diffuse adenomyomatosis of the gallbladder in a child[J]. J Pediatr Hematol Oncol, 2016, 38(8):307-309.
[7] 殷雷, 邱法波, 吴昌亮, 等. 中国近30年胆囊腺肌增生症流行病学特征及诊治经验[J]. 中国现代医学杂志, 2012, 22(18):66-70.
[8] Kim JH, Jeong IH, Han JH, et al. Clinical/pathological analysis of gallbladder adenomyomatosis; type and pathogenesis[J]. Hepatogastroenterology, 2010, 57(99-100):420-425.
[9] Charles H, Pilgrim C, Groeschl RT, et al. Modern perspective on factors predisposing to the development of gallbladder cancer[J]. HPB, 2013, 15(11):839-844.
[10] Pang L, Zhang Y, Wang Y, et al. Pathogenesis of gallbladder adenomyomatosis and its relationship with early-stage gallbladder carcinoma: an overview[J]. Braz J Med Biol Res, 2018, 51(6):7411.
[11] Jacobs E, Ardichvili D, D′Avanzo E, et al. Cyst of the gallbladder[J]. Dig Dis Sci, 1991, 36(12):1976-1802.
[12] 王晓瑾, 龚彪, 别里克·扣肯, 等. 内镜下胰胆管造影术对胆胰管汇合异常的诊断及治疗价值[J]. 内科理论与实践, 2016, 11(1):38-41.
[13] Lee SW, Yun SP, Seo HI. Heterotopic pancreas of the gallbladder associated with segmental adenomyomatosis of the gallbladder[J]. J Korean Surg Soc, 2013, 84(5):309-311.
[14] Suzuki K, Abe K, Ohbu M. A Resected gallbladder carcinoma coexisting with adenomyomatosis involving varied degrees of intraepithelial dysplasia:a case report and li-terature review[J]. Surg Laparosc Endosc Percutan Tech, 2019, 29(4):290-296.
[15] Ootani T, Shirai Y, Tsukada K, et al. Relationship between gallbladder carcinoma and the segmental type of adenomyomatosis of the gallbladder[J]. Cancer, 1992, 69(11):2647-2652.
[16] Nabatame N, Shirai Y, Nishimura A, et al. High risk of gallbladder carcinoma in elderly patients with segmental adenomyomatosis of the gallbladder[J]. J Exp Clin Cancer Res, 2004, 23(4):593-598.
[17] Valle JW. BINGO: targeted therapy for advanced biliary-tract cancer[J]. Lancet Oncol, 2014, 15(8):778-780.
[18] Müller BG, de Aretxabala X, González Domingo M. A review of recent data in the treatment of gallbladder cancer: what we know,what we do,and what should be done[J]. Am Soc Clin Oncol Educ Book, 2014:e165-170.
[19] Ebata T, Ercolani G, Alvaro D, et al. Current status on cholangiocarcinoma and gallbladder cancer[J]. Liver Cancer, 2016, 6(1):59-65.
[20] Lee HJ, Chung WS, Kim JY, et al. Chronic inflammation-related radiological findings of gallbladder adenomyomatosis[J]. Jpn J Radiol, 2020, 38(5):463-471.
[21] Hammad AY, Miura JT, Turaga KK, et al. A literature review of radiological findings to guide the diagnosis of gallbladder adenomyomatosis[J]. HPB (Oxford), 2016, 18(2):129-135.
[22] Miyoshi H, Inui K, Katano Y, et al. B-mode ultrasonographic diagnosis in gallbladder wall thickening[J]. J Med Ultrason (2001), 2021, 48(2):175-186.
[23] Bang SH, Lee JY, Woo H, et al. Differentiating between adenomyomatosis and gallbladder cancer: revisiting a comparative study of high-resolution ultrasound,multidetector CT, and MR imaging[J]. Korean J Radiol, 2014, 15(2):226-234.
[24] Kim HJ, Park JH, Park DI, et al. Clinical usefulness of endoscopic ultrasonography in the differential diagnosis of gallbladder wall thickening[J]. Dig Dis Sci, 2012, 57(2):508-515.
[25] Miwa H, Numata K, Sugimori K, et al. Differential diagnosis of gallbladder polypoid lesions using contrast-enhanced ultrasound[J]. Abdom Radiol(NY), 2019, 44(4):1367-1378.
[26] Negrao de Figueiredo G, Mueller-Peltzer K, Zengel P, et al. Diagnostic perfor-mance of contrast-enhanced ultrasound (CEUS) for the evaluation of gallbladder diseases1[J]. Clin Hemorheol Microcirc, 2018, 69(1-2):83-91.
[27] Chen LD, Huang Y, Xie XH, et al. Diagnostic nomogram for gallbladder wall thickening mimicking malignancy: Using contrast-enhanced ultrasonography or multi-detector computed tomography?[J]. Abdom Radiol(NY), 2017, 42(10):2436-2446.
[28] Gerstenmaier JF, Hoang KN, Gibson RN. Contrast-enhanced ultrasound in gallbladder disease: A pictorial review[J]. Abdom Radiol(NY), 2016, 41(8):1640-1652.
[29] Wang W, Fei Y, Wang F. Meta-analysis of contrast-enhanced ultrasonography for the detection of gallbladder carcinoma[J]. Med Ultrason, 2016, 18(3):281-328.
[30] Tang SS, Huang L, Wang Y, et al. Contrast-enhanced ultrasonography diagnosis of fundal localized type of gallbladder adenomyomatosis[J]. BMC Gastroenterol, 2015, 15:99.
[31] Turkvatan A, Turkoglu MA, Ozogul Y, et al. Multidetector computed tomography diagnosis of adenomyomatosis of the gallbladder[J]. Turk J Gastroenterol, 2013, 24(3):286-289.
[32] Kim BS, Oh JY, Nam KJ, et al. Focal thickening at the fundus of the gallbladder: computed tomography differentiation of fundal type adenomyomatosis and localized chronic cholecystitis[J]. Gut Liver, 2014, 8(2):219-223.
[33] Yang HK, Lee JM, Yu MH, et al. CT diagnosis of gallbladder adenomyomatosis: importance of enhancing mucosal epithelium, the “cotton ball sign”[J]. Eur Radiol, 2018, 28(9):3573-3582.
[34] Bonatti M, Vezzali N, Lombardo F, et al. Gallbladder adenomyomatosis:imaging findings, tricks and pitfalls[J]. Insights Imaging, 2017, 8(2):243-253.
[35] Tomizawa M, Shinozaki F, Fugo K, et al. Negative signals for adenomyomatosis of the gallbladder upon diffusion-weighted whole body imaging with background body signal suppression/T2-weighted image fusion analysis[J]. Exp Ther Med, 2016, 11(5):1777-1780.
[36] Pellino G, Sciaudone G, Candilio G, et al. Stepwise approach and surgery for gallbladder adenomyomatosis: a mini-review[J]. Hepatobiliary Pancreat Dis Int, 2013, 12(2):136-142.
[37] Golse N, Lewin M, Rode A, et al. Gallbladder adenomyomatosis: diagnosis and management[J]. J Visc Surg, 2017, 154(5):345-353.
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