消化内镜在胰腺导管内乳头状黏液性肿瘤诊疗中的应用及进展
收稿日期: 2025-08-15
网络出版日期: 2025-12-09
基金资助
国家自然科学基金(82270667)
Application and advancements of endoscopy in the management of pancreatic intraductal papillary mucinous neoplasm
Received date: 2025-08-15
Online published: 2025-12-09
胰腺导管内乳头状黏液性肿瘤（IPMN）是一种具有恶性潜能的胰腺囊性病变，其管理依赖于准确的诊断、风险分层和监测。内镜技术，尤其是超声内镜（EUS）和内镜逆行胰胆管造影（ERCP），在IPMN的诊断、风险评估和治疗决策中起到重要作用。然而，其应用仍面临技术限制、操作依赖性、成本效益考量及长期监测策略的争议等挑战。本文旨在综述消化内镜技术在IPMN诊疗中的应用现状与最新进展，并探讨其未来在实现个体化精准管理方面的优化方向。
关键词： 胰腺导管内乳头状黏液性肿瘤; 超声内镜; 内镜逆行胰胆管造影
徐琬倩 , 周春华 , 邹多武 . 消化内镜在胰腺导管内乳头状黏液性肿瘤诊疗中的应用及进展[J]. 外科理论与实践, 2025 , 30(05) : 369 -377 . DOI: 10.16139/j.1007-9610.2025.05.01
Pancreatic intraductal papillary mucinous neoplasm (IPMN) is a pancreatic cystic lesion with malignant potential, the management of which relies on accurate diagnosis, risk stratification, and surveillance. Endoscopic techniques, particularly endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP), play crucial roles in the diagnosis, risk assessment, and therapeutic decision-making for IPMN. However, their application still faces challenges including technical limitations, operator dependence, cost-effectiveness considerations, and controversies regarding long-term surveillance strategies.This article comprehensively reviewed the current applications and recent advancements in gastrointestinal endoscopy for managing IPMN, and discussed future directions for refining personalized, precision-based treatment approaches.
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