关键词: 乳房再造, 血流动力学研究, 超回流, 静脉增流

Abstract: Objective To evaluate the efficacy of venous augmentation of DIEP flap in pig and to clarify the hemodynamics. Methods Twenty four female Yorkshire micro-pigs were included. All of the pigs were performed DIEP flap surgery to form DIEP flap and venous augmented DIEP flap, then several hemodynamic indexes between the two different flap types were evaluated and compared, including flap perfusion, venous pressure and venous blood gas analysis. After the analysis of the dynamics, all of the flaps were sutured up, while 12 of the flaps formed venous augmented DIEP flap （experimental group） and the rest 12 pigs formed classic DIEP flap （control group）. The animals were sacrificed at the 7th postoperative day, and the final partial necrosis rate and the survival rate were compared between the two groups. Results Compared to the condition in none venous augmentation, all the dynamic indexes were improved dramatically after the application of venous augmentation. The flap survival rate was （99.4±1.2）% in the experimental group, and （82.1±7.6）% in the control group. There was significant difference between the two groups. Conclusion The venous augmentation technique is effective in promoting the blood perfusion and elevating the viability of DIEP flap. Venous augmentation is a reliable technique to improve flap venous congestion and viability, especially for those large flaps.

Key words: Breast reconstruction, Hemodynamic study, Venous super-drainage, Venous augmentation