3D 生物打印在骨组织血管网络形成中的研究进展

组织工程与重建外科杂志 ›› 2023, Vol. 19 ›› Issue (3): 298-.

3D 生物打印在骨组织血管网络形成中的研究进展

出版日期:2023-06-01 发布日期:2023-07-05

Research progress of three dimensional bio-printing technology for formation of vascular network in bone tissue

Online:2023-06-01 Published:2023-07-05

摘要/Abstract

摘要：

骨移植物的血管化是骨组织工程（Bone tissue engineering，BTE）面临的主要挑战之一。血管化 BTE 构建的

最终目标是提供一个富含功能性血管网络的骨环境，实现高效的骨整合，加速植入后的功能恢复。本文对 3D 生物

打印在骨组织血管网络形成中的研究进展进行综述，详细阐述了血管网络形成机制及 3D 生物打印技术的特点，重

点总结目前 BTE 中的血管化策略，并对其发展前景进行展望。

关键词:

3D 生物打印 , 　骨组织工程 , 　血管网络 , 　血管化

Abstract:

Vascularization of bone grafts is one of the major challenges facing bone tissue engineering (BTE). The ultimate

goal of the construction of vascularized BTE is to provide a bone environment rich in functional vascular networks to achieve

efficient bone integration and accelerate the functional recovery after implantation. In this paper, the research progress of 3D

bio-printing in the formation of vascular network in bone tissue was reviewed, the formation mechanism of vascular network and

the characteristics of 3D bio-printing technology were elaborated, the current vascularization strategies in BTE were summarized,

and its development prospects were prospected.

Key words:

Three dimensional bio-printing technology, 　Bone tissue engineering, 　Vascular network, 　Vascularization

翟传兴　王志梦　王国栋　张元民.

3D 生物打印在骨组织血管网络形成中的研究进展

[J]. 组织工程与重建外科杂志, 2023, 19(3): 298-.

ZHAI Chuanxing, WANG Zhimeng, WANG Guodong, et al.

Research progress of three dimensional bio-printing technology for formation of vascular network in bone tissue [J]. Journal of Tissue Engineering and Reconstructive Surgery, 2023, 19(3): 298-.

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