组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2024, Vol. 20 ›› Issue (1): 83-.

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关节镜下自体骨软骨移植对膝关节局限性软骨损伤的临床疗效评价

  

  • 发布日期:2024-03-07

Clinical efficacy of autologous osteochondral transplantation under arthroscopy for localized cartilage injury of the knee joint

  • Published:2024-03-07

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摘要：

目的　探讨关节镜下自体骨软骨移植术对膝关节局限性软骨损伤的临床疗效，并以磁共振成像（MRI）检查对
疗效进行评价。方法　选取2018年6月至2021年6月诊治的100例膝关节局限性软骨损伤患者，按随机数字表法分为
研究组和对照组，每组各50例。研究组采取关节镜下自体骨软骨移植术，对照组采取微骨折术治疗。采用MRI评估其
手术疗效，并记录其术后膝关节软骨愈合时间；采用Lysholm膝关节功能评分表、国际膝关节文献委员会（IKDC）膝关节
评估表，评估患者治疗前后膝关节功能变化；统计患者术后并发症发生率。结果　研究组关节软骨愈合优良率
98.00%，高于对照组84.00%（P＜0.05）。两组术前和术后3个月的Lysholm评分、IKDC评分比较差异无统计学意义（P＞
0.05）；术后6、12、24个月，研究组Lysholm评分、IKDC评分均高于对照组（P＜0.05）。两组患者术后均无严重并发症，且
并发症发生率差异无统计学意义（P＞0.05）。研究组术后膝关节软骨愈合时间短于对照组（P＜0.05）。结论　关节镜
下自体骨软骨移植术对膝关节局限性软骨损伤的远期治疗效果显著，可有效改善患者术后膝关节功能，缩短膝关节软
骨愈合时间，安全性高。

关键词:

Abstract:

Objective To explore the clinical efficacy of autologous osteochondral transplantation under arthroscopy for localized cartilage injury of the knee joint and evaluate the efficacy by magnetic resonance imaging （MRI）. Methods From June 2018 to June 2021，100 patients with localized cartilage injury of the knee joint were divided into study group and
control group according to random number table method， with 50 cases in each group. The research group underwent
arthroscopic autologous bone and cartilage transplantation， while the control group underwent microfracture surgery. The
surgical efficacy was evaluated using MRI and the healing time of the knee joint cartilage after operation was recorded.
Lysholm knee joint function scoring table and the International Knee Joint Literature Committee （IKDC） scoring table were
used to evaluate the changes of knee function before and after operation. The incidence of postoperative complications was
analyzed. Results The excellent and good rate of articular cartilage healing in the study group was 98.00%， which was
higher than that in the control group 84.00% （P<0.05）. There was no statistically significant difference in Lysholm score and
IKDC score between the two groups before and 3 months after operation （P>0.05）
. At 6，12， and 24 months after operation，the Lysholm score and IKDC score in the study group were higher than those in the control group （P<0.05）. There were no serious postoperative complications between the two groups， and there was no statistically significant difference in the incidence of complications （P>0.05）. The healing time of knee joint cartilage in the study group was shorter than that in the control group after operation （P<0.05）. Conclusion Arthroscopic autologous osteochondral transplantation has a significant long-term therapeutic effect on localized cartilage injury in the knee joint， which can effectively improve postoperative knee joint function and shorten the healing time of knee joint cartilage with high safety.

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