组织工程与重建外科杂志

组织工程与重建外科杂志 ›› 2024, Vol. 20 ›› Issue (2): 199-.

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假体隆乳术后发生包膜挛缩的多因素分析

  

  • 出版日期:2024-04-30 发布日期:2024-05-14

Multivariate analysis of capsular contracture after breast augmentation with prosthesis

  • Online:2024-04-30 Published:2024-05-14

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摘要：

目的　研究假体隆乳术后包膜挛缩发生的相关因素。方法　采用回顾性对照研究的方法，对 2019年 4月到
2020年1月收治的227例硅凝胶假体隆乳手术患者的临床资料进行分析，依据是否发生包膜挛缩分为包膜挛缩组和对
照组。随访24个月，比较两组患者的年龄、BMI、吸烟史、哺乳史、手术入路、假体品牌及表面性状、假体是否选择过大、
是否使用内窥镜、引流量及有无血肿，并对有显著相关性的因素进行回归分析。结果　两组的年龄、BMI、哺乳史、手术
入路、假体品牌、假体表面性状、是否使用内窥镜及引流量等差异均无统计学意义（P＞0.05），吸烟史、假体选择过大及
血肿等因素与包膜挛缩的发生显著相关（P＜0.05）。Logistic回归分析结果显示，在纠正了手术入路、假体表面性状及
是否使用内窥镜后，吸烟史（OR=2.968，95%CI：
1.385~6.365）、假体选择过大（OR=6.028，95%CI：
2.448~14.845）及血肿
（OR=14.560，95%CI：
1.783~118.922）等因素仍与包膜挛缩呈正相关。结论　吸烟史、假体选择过大及血肿增加了包膜
挛缩的发生率，具体机制仍需进一步研究。

关键词:

Abstract:

Objective To explore the related factors of capsular contracture of prosthetic breast augmentation. Methods
A retrospective controlled study was used to analyze the clinical data of 227 patients who underwent breast augmentation with
silicone gel prosthesis from April 2019 to January 2020. According to whether capsule contracture occurred， the patients were
divided into capsule contracture group and control group， followed up for 24 months. The age， BMI， smoking history，
lactation history， surgical approach， prosthesis brand and surface properties， whether prosthesis was too large， whether
endoscope was used， drainage volume and hematoma between the two groups were compared， and regression analysis was
performed for the factors with significant correlation. Results There were no significant differences in age， BMI， lactation
history， surgical approach， brand of prosthesis， surface traits of prosthesis， whether to use endoscope or not and drainage
volume between the two groups （P>0.05）
. Smoking history， oversized prosthesis and hematoma were significantly correlated
with the occurrence of capsular contracture （P<0.05）
. Logistic regression analysis showed that after correcting the surgical
approach， prosthesis surface properties and whether or not to use endoscopy， smoking history （OR=2.968，
95%CI：
1.385-
6.365）， oversized prosthesis （OR=6.028，
95%CI：
2.448-14.845） and hematoma （OR=14.560，
95%CI：
1.783-118.922）
were still positively correlated with capsular contracture. Conclusion Smoking history， excessive prosthesis selection and
hematoma increase the incidence of capsular contracture， and the specific mechanism needs further study.

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