组织工程与重建外科杂志 ›› 2025, Vol. 21 ›› Issue (4): 40-.

• •    下一篇

基于蛋白质组学的肋软骨钙化和吸收问题分析在耳再造手术中的应用研究进展

  

  • 出版日期:2025-08-01 发布日期:2025-09-08

The mechanisms of midfacial anatomical aging and the research progress on midfacial lifting surgery

  • Online:2025-08-01 Published:2025-09-08

摘要:

肋软骨的钙化和吸收问题在耳再造手术中影响着耳部的形态和稳定性。蛋白质组学作为一种新兴的研究领域,逐渐被应用于探索肋软骨钙化和吸收的分子机制。当前,尽管已有一些报道揭示了蛋白质组学在肋软骨钙化和吸收分析中的研究潜力,但相关研究仍处于起步阶段,存在样本量小、研究方法多样化以及结果重复性差等问题。本文旨在综述基于蛋白质组学的肋软骨钙化和吸收分析的最新研究进展,探讨其在耳再造手术中的具体应用,以期为临床实践提供有价值的参考和指导。

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Abstract:

Calcification and absorption of the costal cartilage play an important role in ear reconstruction surgery,affecting the shape and stability of the ear. With the continuous development of medical technology, proteomics, as a new
research field, has been gradually applied to explore the molecular mechanism of costal cartilage calcification and absorption.At present, although some studies have revealed the potential of proteomics in the analysis of costal cartilage calcification and absorption, relevant studies are still in the initial stage, and there are problems such as small sample size, diversified research methods and poor repeatability of results. The purpose of this article is to review the latest research progress of the analysis for costal cartilage calcification and absorption based on proteomics, and to discuss its specific application in ear reconstruction surgery, in order to provide valuable reference and guidance for clinical practice.

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