组织工程与重建外科杂志 ›› 2017, Vol. 13 ›› Issue (2): 82-84.doi: 10.3969/j.issn.1673-0364.2017.02.006

• 论著 • 上一篇    下一篇

头皮神经纤维瘤的外科治疗

文国忠,袁斯明,王慜,徐媛,海曦,崔磊,汪军,洪志坚   

  1. 南京大学医学院附属金陵医院(南京军区南京总医院)烧伤整形科
  • 发布日期:2020-07-23

Surgical Treatment of Scalp Neurofibromas

WEN Guozhong,YUAN Siming,WANG Min,XU Yuan,HAI Xi,CUI Lei,WANG Jun,HONG Zhijian   

  • Published:2020-07-23
  • Contact: 南京总医院科学基金

摘要: 目的 探索头皮神经纤维瘤的个性化外科治疗策略。方法 回顾性分析我科2006年1~6月治疗的35例头皮神经纤维瘤病例,统计瘤体大小,分析治疗方法和结果。本组病例的外科治疗方法包括:(1)瘤体直径<5 cm,切除瘤体,局部头皮瓣转移修复;(2)瘤体直径>5 cm,优先选择扩张器治疗,二期手术切除肿瘤,扩张皮瓣修复创面;如患者拒绝扩张器治疗,也可以直接切除肿瘤,植皮修复创面;(3)瘤体特别巨大,或瘤体内发生出血需尽快手术,术前行动脉造影并超选择栓塞肿瘤营养动脉,栓塞后3 d内切除肿瘤,植皮修复。结果 肿瘤切除局部皮瓣转移修复14例,应用扩张器治疗9例,切除瘤体植皮7例,术前栓塞营养动脉、切除瘤体植皮5例。所有患者均成功切除肿瘤,未发生术中出血过多等危及生命的并发症。部分皮瓣边缘坏死或小面积植皮不成活,经换药后愈合。随访6个月至3年,局部未见瘤体复发。结论对于头皮神经纤维瘤,应根据瘤体具体情况(大小、血供、病灶内有无出血等)选择个性化治疗方法,保障术中安全,保留头皮外观,可取得良好疗效。

关键词: 头皮神经纤维瘤, 皮瓣, 皮片, 扩张器, 介入栓塞

Abstract: Objective To explore the individual surgical treatment strategy for neurofibroma. Methods A retrospective analysis was made on the 35 cases of scalp neurofibroma treated in our clinic from January 2006 to June 2016. The size of the tumor, surgical treatments and results were recorded. The surgical treatments included: ① If the tumor diameter was less than 5 cm, tumor resection and local skin flap transfer was performed. ② If the diameter was more than 5cm, skin expander treatment was preferred. And if the patient refused to use the expander, then tumor resection and skin graft was performed instead. ③ If the tumor was very large or hemorrhage occurred in the tumor, preoperative arteriography and superselective embolization of the tumor's nutrient arteries were conducted, and he tumor resection was performed within 3 days after the embolization. Results Fourteen patients were treated with tumor resection and local skin flap transfer. 9 patients were treated with skin expander. 7 patients were treated with tumor resection and skin graft. 5 patients were treated with preoperative arterial embolization, tumor resection and skin graft. All tumors were successfully removed without intraoperative hemorrhage or other life-threatening complications. Marginal necrosis in partial flap, small area of skin graft which failed to survive, were both healed with dressing changing. All the patients were followed up for 6 months to 3 years, no recurrence was observed. Conclusion For the scalp neurofibroma, individualized surgical treatment selection according to the conditions of the tumor (such as the size, blood supply, intra-tumor hemorrhage, etc.) can ensure the intraoperative safety, preserve the scalp appearance, and so get good results.

Key words: Scalp Neurofibroma, Skin flap, Skin graft, Expander, Interventional embolization

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